Evidence map›Paper›PMID 34162348›Full record

ArticleBMC public health2021

Prevalence of latent tuberculosis infection and feasibility of TB preventive therapy among Thai prisoners: a cross-sectional study.

Sivaporn Gatechompol, Weerakit Harnpariphan, Ruamthip Supanan, Gompol Suwanpimolkul, Jiratchaya Sophonphan, Sasiwimol Ubolyam, Stephen J Kerr, Anchalee Avihingsanon, Kamon Kawkitinarong

Open access · goldAbstract read
In one paragraph

Article in BMC public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 3 pooled it
1.4field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 3 syntheses or guidelines pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Review
  5. Article
  6. Article
  7. Effectiveness of Systematic Screening and Treatment of Tuberculosis in Prison in Thailand.The American journal of tropical medicine and hygiene · 2024
    Article
  8. Occurrence of multidrug-resistantVeterinary world · 2024
    Article
  9. Article
  10. Article
  11. Tuberculosis in Prisons: Importance of Considering the Clustering in the Analysis of Cross-Sectional Studies.International journal of environmental research and public health · 2023
    Article
  12. Review
  13. Review
  14. Correctional Officers' Health Literacy and Practices for Pulmonary Tuberculosis Prevention in Prison.International journal of environmental research and public health · 2022
    Article
  15. Article
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  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Sivaporn GatechompolHIV-NAT, Thai Red Cross AIDS Research Centre, 104 Ratchadamri Rd., Pathumwan, Bangkok, 10330, Thailand. sivaporn.k@hivnat.org.
Weerakit HarnpariphanMedical Correctional Institution, Bangkok and Klong Prem Central Prison, Bangkok, Thailand.
Ruamthip SupananMedical Correctional Institution, Bangkok and Klong Prem Central Prison, Bangkok, Thailand.
Gompol SuwanpimolkulTuberculosis Research Unit, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Jiratchaya SophonphanHIV-NAT, Thai Red Cross AIDS Research Centre, 104 Ratchadamri Rd., Pathumwan, Bangkok, 10330, Thailand.
Sasiwimol UbolyamHIV-NAT, Thai Red Cross AIDS Research Centre, 104 Ratchadamri Rd., Pathumwan, Bangkok, 10330, Thailand.
Stephen J KerrHIV-NAT, Thai Red Cross AIDS Research Centre, 104 Ratchadamri Rd., Pathumwan, Bangkok, 10330, Thailand.
Anchalee AvihingsanonHIV-NAT, Thai Red Cross AIDS Research Centre, 104 Ratchadamri Rd., Pathumwan, Bangkok, 10330, Thailand.
Kamon KawkitinarongTuberculosis Research Unit, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Chulalongkorn University · THHIV Netherlands Australia Thailand Research Collaboration · THKing Chulalongkorn Memorial Hospital · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrisons are considered as major reservoirs for tuberculosis. Preventive therapy for latent TB infection (LTBI) is an adjunctive strategy to control TB. However, LTBI data in Thai prisoners is limited. This study assessed the prevalence of LTBI and feasibility of isoniazid preventive therapy (IPT).

methodsA cross-sectional study was conducted among prisoners in Klong Prem Central Prison, Bangkok. Participants were screened for active TB by questionnaire and chest X-ray. LTBI was evaluated by Tuberculin skin test (TST) and QuantiFERON-TB Gold Plus (QFTP) among subgroup. Participants with positive TST or QFTP were considered to have LTBI. Participants with LTBI were offered IPT.

resultsFrom August 2018-November 2019, 1002 participants were analyzed. All participants were male with a median age of 38 (IQR 32-50) years. LTBI identified by either TST/QFTP was present in 466 (46.5%) participants. TST was positive in 359 (36%) participants. In the subgroup of 294 participants who had both TST and QFTP results, 181/294 (61.6%) tested positive by QFTP. Agreement between TST and QFTP was 55.1% (Kappa = 0.17). The risk factors associated with LTBI were previous incarceration (aOR 1.53, 95%CI, 1.16-2.01, p = 0.002), history of prior active TB (aOR 3.02, 95%CI, 1.74-5.24, p < 0.001) and duration of incarceration ≥10 years (aOR 1.86, 95%CI, 1.24-2.79, p = 0.003). Majority of LTBI participants (82%) agreed to take IPT. Three hundred and 56 (93%) participants completed treatment whereas 27 (7%) participants discontinued IPT due to the side effects of INH.

conclusionThis is the first study to evaluate the prevalence of LTBI and feasibility of IPT among Thai prisoners. LTBI prevalence in male prisoners in Thailand is high. LTBI screening and treatment should be implemented together with other preventive components.

Indexed as

Latent TuberculosisPrisonersAdultCross-Sectional StudiesFeasibility StudiesHumansInterferon-gamma Release TestsMaleMiddle AgedPrevalenceThailandTuberculin TestIGRAInmateIsoniazid preventive therapyLTBITST

Identifiers

PMID34162348
PMCPMC8223292
OpenAlexW3176839016

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.