Evidence map›Paper›PMID 34162217›Full record

ArticleStroke2021

Improving Prehospital Stroke Diagnosis Using Natural Language Processing of Paramedic Reports.

Anoop Mayampurath, Zahra Parnianpour, Christopher T Richards, William J Meurer, Jungwha Lee, Bruce Ankenman, Ohad Perry, Scott J Mendelson, Jane L Holl, Shyam Prabhakaran

Open access · bronzeAbstract read
In one paragraph

Article in Stroke, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 30 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
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  7. Article
  8. Pre-Hospital Stroke Care beyond the MSU.Current neurology and neuroscience reports · 2024
    Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Prehospital stroke management and mobile stroke units.Current opinion in neurology · 2023
    Review
  15. Article
  16. Article
  17. Artificial intelligence decision points in an emergency department.Clinical and experimental emergency medicine · 2022
    Article
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 3 countries.

Anoop MayampurathDepartment of Pediatrics (A.M.), University of Chicago, IL.
Zahra ParnianpourDepartment of Neurology (Z.P., S.J.M., J.L.H., S.P.), University of Chicago, IL.
Christopher T RichardsDepartment of Emergency Medicine, University of Cincinnati, OH (C.T.R.).
William J MeurerDepartment of Emergency Medicine, University of Michigan, Ann Arbor, IL (W.J.M.).
Jungwha LeeDepartment of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (J.L.).
Bruce AnkenmanDepartment of Industrial Engineering and Management Studies, Northwestern University (B.A., O.P.).
Ohad PerryDepartment of Industrial Engineering and Management Studies, Northwestern University (B.A., O.P.).
Scott J MendelsonDepartment of Neurology (Z.P., S.J.M., J.L.H., S.P.), University of Chicago, IL.
Jane L HollDepartment of Neurology (Z.P., S.J.M., J.L.H., S.P.), University of Chicago, IL.
Shyam PrabhakaranDepartment of Neurology (Z.P., S.J.M., J.L.H., S.P.), University of Chicago, IL.
University of Chicago · USNorthwestern University · USUniversity of Cincinnati · USUniversity of Illinois Chicago · USUniversity of Michigan · USUniversity of Northwestern Ohio · USUniversity of the Valley of Atemajac · MX

Funding

Targeted Healthcare Engineering for Systems Interventions in Stroke (THESIS)R18HS027264 · AHRQ · UNIVERSITY OF CHICAGO · PI HOLL, JANE LOUISE, PRABHAKARAN, SHYAM · 2019 to 2022
$2.5M
Enhancing Stroke Prehospital and Emergency Evaluation and Delivery (E-SPEED)R18HS025359 · AHRQ · UNIVERSITY OF CHICAGO · PI PRABHAKARAN, SHYAM · 2018 to 2021
$1.5M
Using Machine Learning to Predict Clinical Deterioration in Hospitalized ChildrenK01HL148390 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI MAYAMPURATH, ANOOP · 2019 to 2023
$738k
MPP+ LIKE N METHYLATED B CARBOLINES AND OXIDATIVE DAMAGEF32NS010723 · NINDS · MEDICAL COLLEGE OF GEORGIA (MCG) · PI GEARHART, DEBRA A · 1999 to 2001
$80k
AHRQ HHS R18 HS025359AHRQ HHS R18 HS027264NHLBI NIH HHS K01 HL148390NINDS NIH HHS F32 NS010723
6 · The paper itself

Abstract

Background and Purpose: Accurate prehospital diagnosis of stroke by emergency medical services (EMS) can increase treatments rates, mitigate disability, and reduce stroke deaths. We aimed to develop a model that utilizes natural language processing of EMS reports and machine learning to improve prehospital stroke identification. Methods: We conducted a retrospective study of patients transported by the Chicago EMS to 17 regional primary and comprehensive stroke centers. Patients who were suspected of stroke by the EMS or had hospital-diagnosed stroke were included in our cohort. Text within EMS reports were converted to unigram features, which were given as input to a support-vector machine classifier that was trained on 70% of the cohort and tested on the remaining 30%. Outcomes included final diagnosis of stroke versus nonstroke, large vessel occlusion, severe stroke (National Institutes of Health Stroke Scale score >5), and comprehensive stroke center-eligible stroke (large vessel occlusion or hemorrhagic stroke). Results: Of 965 patients, 580 (60%) had confirmed acute stroke. In a test set of 289 patients, the text-based model predicted stroke nominally better than models based on the Cincinnati Prehospital Stroke Scale (c-statistic: 0.73 versus 0.67, P=0.165) and was superior to the 3-Item Stroke Scale (c-statistic: 0.73 versus 0.53, P<0.001) scores. Improvements in discrimination were also observed for the other outcomes. Conclusions: We derived a model that utilizes clinical text from paramedic reports to identify stroke. Our results require validation but have the potential of improving prehospital routing protocols.

Indexed as

Natural Language ProcessingAgedAged, 80 and overAllied Health PersonnelChicagoEmergency Medical ServicesFemaleHumansMaleMiddle AgedResearch ReportRetrospective StudiesStrokediagnosismachine learningnatural language processingpatientretrospective studies

Identifiers

PMID34162217
PMCPMC8514137
OpenAlexW3174573842

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.