Evidence map›Paper›PMID 34161982›Full record

Trial reportAmerican journal of critical care : an official publication, American Association of Critical-Care Nurses2021

Patients' Adaptations After Acute Respiratory Distress Syndrome: A Qualitative Study.

Katrina E Hauschildt, Claire Seigworth, Lee A Kamphuis, Catherine L Hough, Marc Moss, Joanne M McPeake, Molly Harrod, Theodore J Iwashyna

Open access · greenAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in American journal of critical care : an official publication, American Association of Critical-Care Nurses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. ICU Recovery Interventions: Is It Time for a Personalized Medicine Approach?American journal of respiratory and critical care medicine · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 2 countries.

Katrina E HauschildtKatrina E. Hauschildt is an advanced fellow in health services research at the Veterans Affairs Center for Clinical Management Research and a research associate in the Pulmonary and Critical Care Division at the University of Michigan, Ann Arbor.
Claire SeigworthClaire Seigworth is research health science specialist at the Veterans Affairs Center for Clinical Management Research, Health Services Research & Development Center of Innovation, Ann Arbor, Michigan.
Lee A KamphuisLee A. Kamphuis is research health science specialist at the Veterans Affairs Center for Clinical Management Research, Health Services Research & Development Center of Innovation, Ann Arbor, Michigan.
Catherine L HoughCatherine L. Hough is a professor of medicine and chief of the Division of Pulmonary and Critical Care Medicine at the Oregon Health & Science University in Portland.
Marc MossMarc Moss is the Roger S. Mitchell Professor of Medicine and division head of Pulmonary Sciences and Critical Care Medicine, University of Colorado School of Medicine, Aurora, Colorado.
Joanne M McPeakeJoanne M. McPeake is a nurse consultant, NHS Greater Glasgow and Clyde, Glasgow Royal Infirmary, Glasgow, United Kingdom, a senior honorary clinical lecturer at the University of Glasgow School of Medicine, Dentistry & Nursing, Glasgow, and a THIS Institute research fellow at the University of Cambridge.
Molly HarrodMolly Harrod is research health science specialist at the Veterans Affairs Center for Clinical Management Research, Health Services Research & Development Center of Innovation, Ann Arbor, Michigan.
Theodore J IwashynaTheodore J. Iwashyna is the co-director of the research core at the Veterans Affairs Center for Clinical Management Research, Health Services Research & Development Center of Innovation, and the Alpheus W. Tucker, MD, Collegiate Professor of Internal Medicine at the University of Michigan, Ann Arbor.
VA Center for Clinical Management Research · USHealth Services Research & Development · USNHS Greater Glasgow and Clyde · GBOregon Health & Science University · USUniversity of Colorado Denver · USUniversity of Michigan–Ann Arbor · US

Funding

Effect of randomization to neuromuscular blockade on physical functional impairment and recovery in ARDSR01HL132232 · NHLBI · UNIVERSITY OF WASHINGTON · PI HOUGH, CATHERINE LEE, IWASHYNA, THEODORE J · 2016 to 2019
$2.9M
Clinical Centers (CC) for the NHLBI Prevention and Early Treatment of Acute LungU01HL123031 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HYZY, ROBERT C, PARK, PAULINE K · 2014 to 2020
$2.6M
Pacific Northwest Clinical Center for the NHLBI PETAL NetworkU01HL123008 · NHLBI · UNIVERSITY OF WASHINGTON · PI HOUGH, CATHERINE LEE, ROBINSON, BRYCE · 2014 to 2020
$2.3M
NHLBI NIH HHS R01 HL132232NHLBI NIH HHS U01 HL123008NHLBI NIH HHS U01 HL123031
6 · The paper itself

Abstract

backgroundMany patients confront physical, cognitive, and emotional problems after acute respiratory distress syndrome (ARDS). No proven therapies for these problems exist, and many patients manage new disability and recovery with little formal support. Eliciting patients' adaptations to these problems after hospitalization may identify opportunities to improve recovery.

objectivesTo explore how patients adapt to physical, cognitive, and emotional changes related to hospitalization for ARDS.

methodsSemistructured interviews were conducted after hospitalization in patients with ARDS who had received mechanical ventilation. This was an ancillary study to a multicenter randomized controlled trial. Consecutive surviving patients who spoke English, consented to follow-up, and had been randomized between November 12, 2017, and April 5, 2018 were interviewed 9 to 16 months after that.

resultsForty-six of 79 eligible patients (58%) participated (mean [range] age, 55 [20-84] years). All patients reported using strategies to address physical, emotional, or cognitive problems after hospitalization. For physical and cognitive problems, patients reported accommodative strategies for adapting to new disabilities and recuperative strategies for recovering previous ability. For emotional issues, no clear distinction between accommodative and recuperative strategies emerged. Social support and previous familiarity with the health care system helped patients generate and use many strategies. Thirty-one of 46 patients reported at least 1 persistent problem for which they had no acceptable adaptation.

conclusionsPatients employed various strategies to manage problems after ARDS. More work is needed to identify and disseminate effective strategies to patients and their families.

Indexed as

Adaptation, PhysiologicalAdaptation, PsychologicalRespiratory Distress SyndromeAdultAgedAged, 80 and overCognitionEmotionsHospitalizationHumansMiddle AgedPhysical Functional PerformanceRespiration, ArtificialYoung Adult

Identifiers

PMID34161982
PMCPMC9214834
OpenAlexW3157749417

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.