ArticlePlant biotechnology journal2021
Insights into the effect of human civilization on Malus evolution and domestication.
Article in Plant biotechnology journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 58 citations in OpenAlex.
- Metabolic reprogramming and functional trade-offs during domestication of Sechium edule.Scientific reports · 2026Article
- 2b-RAD sequencing of Malus florentina populations reveals strong population structure and signals of balancing selection at disease resistance loci.BMC plant biology · 2025Article
- Pan-genome analysis reveals the evolution and diversity of Malus.Nature genetics · 2025Article
- Haplotype-resolved and chromosome-level reference genome assembly ofHorticulture research · 2025Article
- Integrative analysis of genome-wide association studies of polyphenols in apple fruits identifies the MdDof2.4Horticulture research · 2025Article
- Deciphering Plant NLR Genomic Evolution: Synteny-Informed Classification Unveils Insights into TNL Gene Loss.Molecular biology and evolution · 2025Article
- Natural variation in MdNAC5 contributes to fruit firmness and ripening divergence in apple.Horticulture research · 2025Article
- An InDel variant in the promoter of the NAC transcription factor MdNAC18.1 plays a major role in apple fruit ripening.The Plant cell · 2024Article
- Why we thrive beneath a northern sky - genomic signals of selection in apple for adaptation to northern Sweden.Heredity · 2024Article
- Article
- The potential range of west Asian apple species Malus orientalis Uglitzk. under climate change.BMC plant biology · 2024Article
- Molecular Structure and Variation Characteristics of the Plastomes from SixBiomolecules · 2023Article
- 4-methylumbelliferone (4-MU) enhances drought tolerance of apple by regulating rhizosphere microbial diversity and root architecture.Horticulture research · 2023Article
- A metabolic perspective of selection for fruit quality related to apple domestication and improvement.Genome biology · 2023Article
- Quantitative Traits of Interest in Apple Breeding and Their Implications for Selection.Plants (Basel, Switzerland) · 2023Article
- Genetic analysis and QTL mapping of aroma volatile compounds in the apple progeny 'Fuji' × 'Cripps Pink'.Frontiers in plant science · 2023Article
- Domestication and selection footprints in Persian walnuts (Juglans regia).PLoS genetics · 2022Article
- Chromosome-scale reference genome provides insights into the genetic origin and grafting-mediated stress tolerance of Malus prunifolia.Plant biotechnology journal · 2022Article
- Root Breeding in the Post-Genomics Era: From Concept to Practice in Apple.Plants (Basel, Switzerland) · 2022Review
- Study on SupergenusPlants (Basel, Switzerland) · 2022Review
Corrections and comments
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Authors and funding
22 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The evolutionary history of the Malus genus has not been well studied. In the current study, we presented genetic evidence on the origin of the Malus genus based on genome sequencing of 297 Malus accessions, revealing the genetic relationship between wild species and cultivated apples. Our results demonstrated that North American and East Asian wild species are closer to the outgroup (pear) than Central Asian species, and hybrid species including natural (separated before the Pleistocene, about 2.5 Mya) and artificial hybrids (including ornamental trees and rootstocks) are between East and Central Asian wild species. Introgressions from M. sylvestris in cultivated apples appeared to be more extensive than those from M. sieversii, whose genetic background flowed westward across Eurasia and eastward to wild species including M. prunifolia, M. × asiatica, M. × micromalus, and M. × robust. Our results suggested that the loss of ancestral gene flow from M. sieversii in cultivated apples accompanied the movement of European traders around the world since the Age of Discovery. Natural SNP variations showed that cultivated apples had higher nucleotide diversity than wild species and more unique SNPs than other apple groups. An apple ERECTA-like gene that underwent selection during domestication on 15
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.