Trial reportCancer2021
Loneliness and mental health during the COVID-19 pandemic in older breast cancer survivors and noncancer controls.
Trial report in Cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
51 citing papers in PubMed, 1 synthesis or guideline pooled it, 80 citations in OpenAlex.
- The Impact of the COVID-19 Pandemic on Mental Health and Cognitive Function in Patients With Cancer: A Systematic Literature Review.Cancer reports (Hoboken, N.J.) · 2024Pooled it
- Trial
- Loneliness and mental health during the COVID-19 pandemic in older breast cancer survivors and noncancer controls.Cancer · 2021Trial
- Social isolation and overall well-being among cancer survivors in the Cancer Prevention Study-3.Journal of cancer survivorship : research and practice · 2026Article
- The Impact of Time and Place on BREAST-Q REACT: A Multi-Institutional Examination.Journal of surgical oncology · 2026Article
- The Experience of Depression in Older Adults With Cancer: A Qualitative Descriptive Analysis.Psycho-oncology · 2026Article
- The Relationship Between Diagnosed Cancer and Self-Reported Distress and Depression: A Cross-Sectional Study Using the 2020 Medical Expenditure Panel Survey.Psycho-oncology · 2026Article
- Moderated mediating effects of perceived loneliness and economic burden between social support and mental health for lung cancer patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Validation of the Spanish version of the social and emotional loneliness scale for adults - short form (SELSA-S) in older adults.BMC research notes · 2026Article
- Association between loneliness and social isolation and health outcomes among cancer survivors and non-cancer controls.Frontiers in aging · 2026Article
- Analysis of loneliness and its related factors in patients undergoing peripheral blood stem cell transplantation.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
- Loneliness and Biomarkers of Alzheimer's Disease, Axonal Damage, and Astrogliosis: A Coordinated Analysis of Two Longitudinal Cohorts.The journals of gerontology. Series B, Psychological sciences and social sciences · 2025Article
- Article
- Global Trends and Research Hotspots in Social Isolation Among Cancer Patients: A Bibliometric Analysis (2005-2024).Journal of multidisciplinary healthcare · 2025Review
- Retrospective Impact of COVID-19 Pandemic on Primary Breast Cancer Care.Breast care (Basel, Switzerland) · 2024Review
- A Biobehavioral Perspective on Caring for Allogeneic Hematopoietic Stem Cell Transplant Survivors with Graft-Versus-Host Disease.Transplantation and cellular therapy · 2024Article
- Loneliness as a predictor of mortality in cancer patients, a cohort studyBiomedica : revista del Instituto Nacional de Salud · 2024Article
- Prevalence of loneliness and associations with health behaviours and body mass index in 5835 people living with and beyond cancer: a cross-sectional study.BMC public health · 2024Article
- Loneliness and fearfulness are associated with non-fatal drug overdose among people who inject drugs.PloS one · 2024Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
19 authors at 10 institutions in 1 country.
Funding
Abstract
backgroundThe coronavirus disease 2019 (COVID-19) pandemic has had wide-ranging health effects and increased isolation. Older with cancer patients might be especially vulnerable to loneliness and poor mental health during the pandemic.
methodsThe authors included active participants enrolled in the longitudinal Thinking and Living With Cancer study of nonmetastatic breast cancer survivors aged 60 to 89 years (n = 262) and matched controls (n = 165) from 5 US regions. Participants completed questionnaires at parent study enrollment and then annually, including a web-based or telephone COVID-19 survey, between May 27 and September 11, 2020. Mixed-effects models were used to examine changes in loneliness (a single item on the Center for Epidemiologic Studies-Depression [CES-D] scale) from before to during the pandemic in survivors versus controls and to test survivor-control differences in the associations between changes in loneliness and changes in mental health, including depression (CES-D, excluding the loneliness item), anxiety (the State-Trait Anxiety Inventory), and perceived stress (the Perceived Stress Scale). Models were adjusted for age, race, county COVID-19 death rates, and time between assessments.
resultsLoneliness increased from before to during the pandemic (0.211; P = .001), with no survivor-control differences. Increased loneliness was associated with worsening depression (3.958; P < .001) and anxiety (3.242; P < .001) symptoms and higher stress (1.172; P < .001) during the pandemic, also with no survivor-control differences.
conclusionsCancer survivors reported changes in loneliness and mental health similar to those reported by women without cancer. However, both groups reported increased loneliness from before to during the pandemic that was related to worsening mental health, suggesting that screening for loneliness during medical care interactions will be important for identifying all older women at risk for adverse mental health effects of the pandemic.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.