SynthesisRevista do Instituto de Medicina Tropical de Sao Paulo2021
Antimicrobial treatment of Corynebacterium striatum invasive infections: a systematic review.
Synthesis in Revista do Instituto de Medicina Tropical de Sao Paulo, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
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Who cites it
43 citing papers in PubMed, 59 citations in OpenAlex.
- Epidemiological and molecular characterization of multidrug-resistantMicrobiology spectrum · 2026Article
- A Case Report of Non-toxigenic Corynebacterium belfantii With Suspected Diphtheria Infection.Cureus · 2026Article
- Infectious Endocarditis Caused by Multidrug-resistant Corynebacterium striatum in an Immunocompetent Host without a History of Cardiac Disease.Internal medicine (Tokyo, Japan) · 2026Article
- Multidrug-resistant Corynebacterium striatum-induced severe pneumonia complicated with multiple organ failure: a diagnostic breakthrough guided by phagocytosis and therapeutic strategy.BMC infectious diseases · 2026Article
- Emerging Role of Corynebacterium in Breast Abscesses: Clinical Profiles, Resistance Patterns, and Recommendations.Cureus · 2026Article
- The Pathogenesis, Clinical Features, and Treatment ofMicroorganisms · 2026Review
- Genomic and clinical insights into multidrug-resistantFrontiers in microbiology · 2026Article
- Article
- A single-center study on epidemiology, microbial distribution, and mortality predictors in catheter-related bloodstream infections.BMC infectious diseases · 2025Article
- Article
- Diphtheria-like PseudomembranousReports (MDPI) · 2025Article
- Evaluating the diagnostic significance of biomarkers in ventriculitis through a multivariate correlation study in a tertiary care center.Scientific reports · 2025Observational
- Deciphering Bacterial Community Succession and Pathogen Dynamics in ICU Ventilator Circuits Through Full-Length 16S rRNA Sequencing for Mitigating the Risk of Nosocomial Infections.Microorganisms · 2025Article
- Relapsing peritoneal dialysis-associated peritonitis caused by Corynebacterium striatum: a case report.CEN case reports · 2025Article
- Metagenomic next-generation sequencing for the diagnosis of Corynebacterium striatum meningitis: case report and literature review.BMC neurology · 2025Review
- Antimicrobial therapy using vancomycin and therapeutic drug monitoring (TDM) in patient with bacteremia caused by Arthrobacter woluwensis:a case report.Journal of pharmaceutical health care and sciences · 2025Article
- Rapid Plasmid-Mediated Acquisition of Erythromycin Resistance viaInfection and drug resistance · 2025Article
- ThePeerJ · 2025Review
- Clinical Characteristics and Risk Factors ofThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2025Article
- Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study was to establish an evidence-based guideline for the antibiotic treatment of Corynebacterium striatum infections. Several electronic databases were systematically searched for clinical trials, observational studies or individual cases on patients of any age and gender with systemic inflammatory response syndrome, harboring C. striatum isolated from body fluids or tissues in which it is not normally present. C. striatum had to be identified as the only causative agent of the invasive infection, and its isolation from blood, body fluids or tissues had to be confirmed by one of the more advanced diagnostic methods (biochemical methods, mass spectrometry and/or gene sequencing). This systematic review included 42 studies that analyzed 85 individual cases with various invasive infections caused by C. striatum. More than one isolate of C. striatum exhibited 100% susceptibility to vancomycin, linezolid, teicoplanin, piperacillin-tazobactam, amoxicillin-clavulanate and cefuroxime. On the other hand, some strains of this bacterium showed a high degree of resistance to fluoroquinolones, to the majority majority of β-lactams, aminoglycosides, macrolides, lincosamides and cotrimoxazole. Despite the antibiotic treatment, fatal outcomes were reported in almost 20% of the patients included in this study. Gene sequencing methods should be the gold standard for the identification of C. striatum, while MALDI-TOF and the Vitek system can be used as alternative methods. Vancomycin should be used as the antibiotic of choice for the treatment of C. striatum infections, in monotherapy or in combination with piperacillin-tazobactam. Alternatively, linezolid, teicoplanin or daptomycin may be used in severe infections, while amoxicillin-clavulanate may be used to treat mild infections caused by C. striatum.
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