Evidence map›Paper›PMID 34161434›Full record

ArticleActa cirurgica brasileira2021

Effects of nandrolone decanoate on femur morphology. Experimental study.

Diogo Benchimol de Souza, Flavia Bittencourt Brasil, Roger Gaspar Marchon, Bruno Félix-Patrício

Open access · goldAbstract read
In one paragraph

Article in Acta cirurgica brasileira, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Anabolic Steroids in Fattening Food-Producing Animals-A Review.Animals : an open access journal from MDPI · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Diogo Benchimol de SouzaPhD. Urogenital Research Unit - Universidade do Estado do Rio de Janeiro - Rio de Janeiro (RJ), Brazil.ORCID http://orcid.org/0000-0003-3456-5029
Flavia Bittencourt BrasilPhD. Laboratory for Research on Translational Histomorphometry - Nature Science Department - Universidade Federal Fluminense - Rio das Ostras (RJ), Brazil.ORCID http://orcid.org/0000-0002-4968-0380
Roger Gaspar MarchonMSc. Urogenital Research Unit - Universidade do Estado do Rio de Janeiro - Rio de Janeiro (RJ), Brazil.ORCID http://orcid.org/0000-0003-0090-5144
Bruno Félix-PatrícioPhD. Laboratory for Research on Translational Histomorphometry - Nature Science Department - Universidade Federal Fluminense - Rio das Ostras (RJ), Brazil.ORCID http://orcid.org/0000-0002-6689-759X
Universidade do Estado do Rio de Janeiro · BRUniversidade Federal Fluminense · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the immediate and late effects of nandrolone on femur morphology of rats.

methodsTwenty-eight animals with 20 weeks of age were divided into four groups: C28, control animals that were euthanized eight weeks after the experiment started; C40, control animals euthanized 20 weeks after the experiment started; T28, treated animals receiving nandrolone during eight weeks and euthanized immediately after the treatment period; and T40, animals treated during eight weeks and euthanized 12 weeks after the end of the treatment. Treated animals received nandrolone decanoate during eight weeks and control groups received peanut oil by intramuscular injection. After euthanasia, femurs were removed, dissected, weighted and measured by digital pachymeter.

resultsThe T40 group presented an increase on distal epiphysis diameter when compared to C40 group. There was no difference between treated and control groups in relation to body and femur absolute weight, relative weight and length of femur. There was also no difference in relation to diameter of proximal epiphysis and diameter of diaphysis among the groups.

conclusionsNandrolone decanoate does not produce significant effect on femur, exception on its distal extremity at late period. The effects of such drug may depend on the time after administration.

Indexed as

Anabolic AgentsNandroloneAnimalsFemurNandrolone DecanoateRatsAnabolic AgentsNandroloneNandrolone Decanoate

Identifiers

PMID34161434
PMCPMC8221801
OpenAlexW3174154262

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.