Evidence map›Paper›PMID 34161135›Full record

ArticleAJR. American journal of roentgenology2021

Mammographic Variation Measures, Breast Density, and Breast Cancer Risk.

John Heine, Erin Fowler, Christopher G Scott, Matthew R Jensen, John Shepherd, Carrie B Hruska, Stacey J Winham, Kathleen R Brandt, Fang F Wu, Aaron D Norman and 4 more

Open access · greenAbstract read
In one paragraph

Article in AJR. American journal of roentgenology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. AI for Breast Cancer Risk Prediction Beyond Breast Density.Journal of the Korean Society of Radiology · 2026
    Review
  3. Article
  4. Reproductive Factors Related to Childbearing and a Novel Automated Mammographic Measure, V.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2024
    Article
  5. Article
  6. Article
  7. Breast Density Analysis Using Digital Breast Tomosynthesis.bioRxiv : the preprint server for biology · 2023
    Article
  8. Associations of Oral Contraceptives with Mammographic Breast Density in Premenopausal Women.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

John HeineDepartment of Cancer Epidemiology, Moffitt Cancer Center, Tampa, FL.
Erin FowlerDepartment of Cancer Epidemiology, Moffitt Cancer Center, Tampa, FL.
Christopher G ScottDepartment of Quantitative Health Sciences, Divisions of Clinical Trials and Biostatistics and Computational Biology, Mayo Clinic, Rochester, MN.
Matthew R JensenDepartment of Quantitative Health Sciences, Divisions of Clinical Trials and Biostatistics and Computational Biology, Mayo Clinic, Rochester, MN.
John ShepherdDepartment of Epidemiology, University of Hawaii Cancer Center, Honolulu, HI.
Carrie B HruskaDepartment of Radiology, Mayo Clinic, Rochester, MN.
Stacey J WinhamDepartment of Quantitative Health Sciences, Divisions of Clinical Trials and Biostatistics and Computational Biology, Mayo Clinic, Rochester, MN.
Kathleen R BrandtDepartment of Radiology, Mayo Clinic, Rochester, MN.
Fang F WuDepartment of Quantitative Health Sciences, Divisions of Clinical Trials and Biostatistics and Computational Biology, Mayo Clinic, Rochester, MN.
Aaron D NormanDepartment of Quantitative Health Sciences, Divisions of Clinical Trials and Biostatistics and Computational Biology, Mayo Clinic, Rochester, MN.
Vernon S PankratzDepartment of Internal Medicine and Biochemistry, University of New Mexico Health Sciences Center, Albuquerque, NM.
Diana L MigliorettiDepartment of Public Health Sciences, Division of Biostatistics, University of California, Davis, Davis, CA.
Karla KerlikowskeDepartments of Medicine and Epidemiology and Biostatistics, University of California at San Francisco, San Francisco, CA.
Celine M VachonDepartment of Quantitative Health Sciences, Division of Epidemiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905.
Mayo Clinic in Arizona · USMoffitt Cancer Center · USKaiser Permanente Washington Health Research Institute · USUniversity of Hawaii Cancer Center

Funding

Risk-based Imaging Strategies to Improve Breast Cancer Surveillance OutcomesP01CA154292 · NCI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Diana L Miglioretti · 2011 to 2026
$52.9M
Quantitative Imaging Clinical Validation Center at Moffitt Cancer CenterU01CA200464 · NCI · H. LEE MOFFITT CANCER CTR & RES INST · PI JOHN J HEINE, Matthew B. Schabath · 2016 to 2026
$9.2M
Automated Density Measures for Estimating Breast Cancer Risk and Therapy ResponseR01CA177150 · NCI · MAYO CLINIC ROCHESTER · PI KERLIKOWSKE, KARLA M, VACHON, CELINE M · 2013 to 2017
$3.0M
Automated Quantitative Measures of Breast DensityR01CA166269 · NCI · H. LEE MOFFITT CANCER CTR & RES INST · PI HEINE, JOHN J · 2013 to 2016
$2.5M
NCI NIH HHS P01 CA154292NCI NIH HHS R01 CA166269NCI NIH HHS R01 CA177150NCI NIH HHS U01 CA200464
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Breast DensityAdultBreastBreast NeoplasmsCase-Control StudiesFemaleHumansMammographyReproducibility of Resultsbreast cancerrisk predictionvariation measuresvolumetric breast density

Identifiers

PMID34161135
PMCPMC9009534
OpenAlexW3176910389

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.