ReviewJournal of endocrinological investigation2021
Frequently asked questions and answers (if any) in patients with adrenal incidentaloma.
Review in Journal of endocrinological investigation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 3 syntheses or guidelines pooled it, 34 citations in OpenAlex.
- Who and how to screen for Cushing's syndrome: the position statement of the Italian Society of Endocrinology.Journal of endocrinological investigation · 2026Guideline
- Second-line tests in the differential diagnosis of neoplastic and non-neoplastic hypercortisolism: a systematic review and meta-analysis.Journal of endocrinological investigation · 2023Pooled it
- Diagnostic Accuracy of CT Texture Analysis in Adrenal Masses: A Systematic Review.International journal of molecular sciences · 2022Pooled it
- Adrenal Incidentaloma: From Silent Diagnosis to Clinical Challenge.Biomedicines · 2025Review
- Who and how to screen for endogenous hypercortisolism in a high-risk population: a special issue of the journal of endocrinological investigations.Journal of endocrinological investigation · 2025Article
- Relationship of obesity, body fat, benign adrenal tumors and the mediating mechanism: a two-step mendelian randomization study.BMC cancer · 2025Article
- Diagnosis and management of adrenal incidentaloma: use of clinical judgment and evidence in dialog with the patient.Surgery today · 2024Review
- Development of diagnostic algorithm for Cushing's syndrome: a tertiary centre experience.Journal of endocrinological investigation · 2024Article
- Article
- Could CT Radiomic Analysis of Benign Adrenal Incidentalomas Suggest the Need for Further Endocrinological Evaluation?Current oncology (Toronto, Ont.) · 2024Article
- Are comorbidities of patients with adrenal incidentaloma tied to sex?Frontiers in endocrinology · 2024Article
- High prevalence of adrenal cortical adenomas in patients with cerebral meningiomas.Journal of endocrinological investigation · 2023Article
- CT Texture Analysis of Adrenal Pheochromocytomas: A Pilot Study.Current oncology (Toronto, Ont.) · 2023Article
- Tumour size in adrenal tumours: its importance in the indication of adrenalectomy and in surgical outcomes-a single-centre experience.Journal of endocrinological investigation · 2022Article
- Cardiovascular risk factors in mild adrenal autonomous cortisol secretion in a Caucasian population.Endocrine connections · 2022Article
- Article
- Modulation of Autophagy in Adrenal Tumors.Frontiers in endocrinology · 2022Review
- Attenuation Value in Adrenal Incidentalomas: A Longitudinal Study.Frontiers in endocrinology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeAdrenal incidentalomas (AIs) are incidentally discovered adrenal masses, during an imaging study undertaken for other reasons than the suspicion of adrenal disease. Their management is not a minor concern for patients and health-care related costs, since their increasing prevalence in the aging population. The exclusion of malignancy is the first question to attempt, then a careful evaluation of adrenal hormones is suggested. Surgery should be considered in case of overt secretion (primary aldosteronism, adrenal Cushing's Syndrome or pheochromocytoma), however the management of subclinical secretion is still a matter of debate.
methodsThe aim of the present narrative review is to offer a practical guidance regarding the management of AI, by providing evidence-based answers to frequently asked questions.
conclusionThe clinical experience is of utmost importance: a personalized diagnostic-therapeutic approach, based upon multidisciplinary discussion, is suggested.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.