Evidence map›Paper›PMID 34160473›Full record

ArticleOpen forum infectious diseases2021

Clinical Efficacy of Patients With Secondary Bacteremia Treated With Omadacycline: Results From Phase 3 Acute Bacterial Skin and Skin Structure Infections and Community-Acquired Bacterial Pneumonia Studies.

George Sakoulas, Paul B Eckburg, Maria Amodio-Groton, Amy Manley, Evan Tzanis, Anita F Das, Robert Noble, Paul C McGovern

Open access · goldAbstract read
In one paragraph

Article in Open forum infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

George SakoulasUniversity of California, San Diego, California, USA.
Paul B EckburgParatek Pharmaceuticals Inc., King of Prussia, Philadelphia, USA.
Maria Amodio-GrotonParatek Pharmaceuticals Inc., King of Prussia, Philadelphia, USA.
Amy ManleyParatek Pharmaceuticals Inc., King of Prussia, Philadelphia, USA.
Evan TzanisParatek Pharmaceuticals Inc., King of Prussia, Philadelphia, USA.
Anita F DasAD Stats Consulting, Guerneville, California, USA.
Robert NobleParatek Pharmaceuticals Inc., King of Prussia, Philadelphia, USA.
Paul C McGovernParatek Pharmaceuticals Inc., King of Prussia, Philadelphia, USA.
Paratek Pharmaceuticals (United States) · USUniversity of California, San Diego · USWest County Health Centers · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this post hoc analysis of the 63 patients with secondary bacteremia enrolled in the 3 omadacycline phase 3 studies of acute bacterial skin/skin structure infections (ABSSSI) and community-acquired bacterial pneumonia (CABP), we determined that omadacycline is a viable therapeutic option for appropriate patients with secondary bacteremia.

Indexed as

acute bacterial skin and skin structure infectionscommunity-acquired pneumoniaefficacyomadacyclinesecondary bacteremia

Identifiers

PMID34160473
PMCPMC8212941
OpenAlexW3177064328

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.