Evidence map›Paper›PMID 34160236›Full record

ArticlemSphere2021

Both Pseudomonas aeruginosa and Candida albicans Accumulate Greater Biomass in Dual-Species Biofilms under Flow.

Swetha Kasetty, Dallas L Mould, Deborah A Hogan, Carey D Nadell

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Review
  3. BioMed research international · 2026
    Review
  4. Article
  5. Article
  6. mBio · 2025
    Article
  7. Microbiology spectrum · 2025
    Article
  8. Article
  9. Simulated Media for Mimicking the Human Environment In Vitro.APMIS : acta pathologica, microbiologica, et immunologica Scandinavica · 2025
    Review
  10. Article
  11. Article
  12. Deciphering microbiome and fungi-bacteria interactions in chronic wound infections using metagenomic sequencing.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2024
    Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Cell arrangement impacts metabolic activity and antibiotic tolerance inbioRxiv : the preprint server for biology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Swetha KasettyDepartment of Biological Sciences, Dartmouth, Hanover, New Hampshire, USA.
Dallas L MouldDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.
Deborah A HoganDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.
Carey D NadellDepartment of Biological Sciences, Dartmouth, Hanover, New Hampshire, USA.
Dartmouth College · US

Funding

Understanding the role of RNA-binding protein mutations in cancerP20GM113132 · NIGMS · DARTMOUTH COLLEGE · PI MADDEN, DEAN R · 2016 to 2025
$25.9M
Translational Research CoreP30DK117469 · NIDDK · DARTMOUTH COLLEGE · PI DEAN R MADDEN · 2018 to 2026
$13.9M
HOST-MICROBE INTERACTIONST32AI007519 · NIAID · DARTMOUTH COLLEGE · PI DEBORAH A HOGAN · 1997 to 2026
$5.9M
Evolved Heterogeneity Contributes to Chronic Fungal Lung InfectionsR01AI127548 · NIAID · DARTMOUTH COLLEGE · PI HOGAN, DEBORAH A · 2017 to 2025
$3.9M
Hypoxia Adaptation and Fungal Virulence of Aspergillus fumigatusR01AI081838 · NIAID · MONTANA STATE UNIVERSITY - BOZEMAN · PI CRAMER, ROBERT ANDREW · 2009 to 2017
$2.9M
NIAID NIH HHS R01 AI081838NIAID NIH HHS R01 AI127548NIAID NIH HHS T32 AI007519NIDDK NIH HHS P30 DK117469NIGMS NIH HHS P20 GM113132
6 · The paper itself

Abstract

Microbe-microbe interactions can strongly influence growth and biofilm formation kinetics. For Pseudomonas aeruginosa and Candida albicans, which are found together in diverse clinical sites, including urinary and intravenous catheters and the lungs of individuals with cystic fibrosis (CF), we compared the kinetics of biofilm formation by each species in dual-species and single-species biofilms. We engineered fluorescent protein constructs for P. aeruginosa (producing

Indexed as

BiomassMicrobial InteractionsBiofilmsCandida albicansCulture MediaCystic FibrosisHumansKineticsPseudomonas aeruginosaPseudomonas InfectionsSingle-Cell AnalysisCulture Mediaartificial sputumbiofilmCandida albicansconfocal microscopycystic fibrosisflowimage analysismicrofluidicspopulation dynamicsPseudomonas aeruginosaspatial ecology

Identifiers

PMID34160236
PMCPMC8265656
OpenAlexW3175122704

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.