Evidence map›Paper›PMID 34160234›Full record

ArticlemSphere2021

Measurement of Klebsiella Intestinal Colonization Density To Assess Infection Risk.

Yuang Sun, Alieysa Patel, John SantaLucia, Emily Roberts, Lili Zhao, Keith Kaye, Krishna Rao, Michael A Bachman

Abstract read
In one paragraph

Article in mSphere, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Article
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  3. Article
  4. Review
  5. Article
  6. Article
  7. A Novel Technique to CharacterizebioRxiv : the preprint server for biology · 2025
    Article
  8. Development of a mouse model forMicrobiology spectrum · 2025
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  9. Article
  10. Article
  11. mBio · 2025
    Article
  12. Review
  13. High Prevalence of Carbapenem-resistantOpen forum infectious diseases · 2024
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Type-2 diabetes mellitus enhancesbioRxiv : the preprint server for biology · 2024
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yuang SunDepartment of Pathology, University of Michigan Medical School, Michigan Medicine, Ann Arbor, Michigan, USA.
Alieysa PatelDepartment of Pathology, University of Michigan Medical School, Michigan Medicine, Ann Arbor, Michigan, USA.
John SantaLuciaDNA Software, Inc., Plymouth, Michigan, USA.
Emily RobertsDepartment of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, Michigan, USA.
Lili ZhaoDepartment of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, Michigan, USA.
Keith KayeDivision of Infectious Diseases, Department of Internal Medicine, University of Michigan Medical School, Michigan Medicine, Ann Arbor, Michigan, USA.
Krishna RaoDivision of Infectious Diseases, Department of Internal Medicine, University of Michigan Medical School, Michigan Medicine, Ann Arbor, Michigan, USA.
Michael A BachmanDepartment of Pathology, University of Michigan Medical School, Michigan Medicine, Ann Arbor, Michigan, USA.

Funding

Integrated modeling of Klebsiella pneumoniae infections based on bacterial genotype, patient factors and colonization statusR01AI125307 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BACHMAN, MICHAEL ABBOTT · 2017 to 2021
$2.6M
NIAID NIH HHS R01 AI125307
6 · The paper itself

Abstract

Klebsiella pneumoniae and the closely related species K. variicola and K. quasipneumoniae are common causes of health care-associated infections, and patients frequently become infected with their intestinal colonizing strain. To assess the association between Klebsiella colonization density and subsequent infections, a case-control study was performed. A multiplex quantitative PCR (qPCR) assay was developed and validated to quantify Klebsiella (K. pneumoniae,

Indexed as

AgedBacteremiaCase-Control StudiesCross InfectionDNA, BacterialFemaleGastrointestinal MicrobiomeHumansIntestinesKlebsiellaKlebsiella InfectionsMaleMiddle AgedMultiplex Polymerase Chain ReactionRectumRisk FactorsDNA, Bacterialdominanceinfection riskintestinal colonizationKlebsiellamicrobiomeqPCR

Identifiers

PMID34160234
PMCPMC8265666

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.