Evidence map›Paper›PMID 34159978›Full record

ArticleChemical communications (Cambridge, England)2021

Imidazolium labelling permits the sensitive mass-spectrometric detection of

Yao-Yao Zhang, Mattia Ghirardello, Ting Wang, Ai-Min Lu, Li Liu, Josef Voglmeir, M Carmen Galan

Open access · hybridAbstract read
In one paragraph

Article in Chemical communications (Cambridge, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 3 countries.

Yao-Yao ZhangGlycomics and Glycan Bioengineering Research Center (GGBRC), College of Food Science and Technology, Nanjing Agricultural University, 1 Weigang, 210095 Nanjing, China. josef.voglmeir@njau.edu.cn.
Mattia GhirardelloSchool of Chemistry, University of Bristol, Cantock's Close, BS8 1TS Bristol, UK. m.c.galan@bristol.ac.uk.ORCID http://orcid.org/0000-0002-2855-4801
Ting WangGlycomics and Glycan Bioengineering Research Center (GGBRC), College of Food Science and Technology, Nanjing Agricultural University, 1 Weigang, 210095 Nanjing, China. josef.voglmeir@njau.edu.cn.
Ai-Min LuCollege of Sciences, Nanjing Agricultural University, 1 Weigang, 210095 Nanjing, China.
Li LiuGlycomics and Glycan Bioengineering Research Center (GGBRC), College of Food Science and Technology, Nanjing Agricultural University, 1 Weigang, 210095 Nanjing, China. josef.voglmeir@njau.edu.cn.ORCID http://orcid.org/0000-0002-2178-9237
Josef VoglmeirGlycomics and Glycan Bioengineering Research Center (GGBRC), College of Food Science and Technology, Nanjing Agricultural University, 1 Weigang, 210095 Nanjing, China. josef.voglmeir@njau.edu.cn.ORCID http://orcid.org/0000-0002-4096-4926
M Carmen GalanSchool of Chemistry, University of Bristol, Cantock's Close, BS8 1TS Bristol, UK. m.c.galan@bristol.ac.uk.ORCID http://orcid.org/0000-0001-7307-2871
Nanjing Agricultural University · CNUniversity of Bristol · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A novel imidazolium derivative (GITag) shows superior ionisation and consequently allows increased mass spectrometric detection capabilities of oligosaccharides and N-glycans. Here we demonstrate that human serum samples can be directly labelled by GITag on a MALDI target plate, abrogating prevalently required sample pretreatment or clean-up steps.

Indexed as

AcetylglucosamineAminationGlycosidesHumansImidazolesLactoseLimit of DetectionSpectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationAcetylglucosamineGlycosidesImidazolesLactose

Identifiers

PMID34159978
PMCPMC8280963
OpenAlexW3174665547

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.