Evidence map›Paper›PMID 34159840›Full record

ArticleChronic illness2022

Multimorbidity groups based on numbers of chronic conditions are associated with daily activity.

Tara C Klinedinst, Lauren Terhorst, Juleen Rodakowski

Open access · hybridAbstract read
In one paragraph

Article in Chronic illness, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Associations Between ACO Enrollment Status and Drug and Nondrug Costs Among Older Adults Newly Diagnosed With ADRD.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2026
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  5. Risk Factors Associated With Progression to Clinical Candida auris Infection Among Adults With Previous Colonization-Florida, 2019-2023.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026
    Article
  6. Article
  7. Article
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Tara C KlinedinstNational Rehabilitation Research and Training Center on Family Support, Health Policy Institute, University of Pittsburgh, Pittsburgh, PA, USA.ORCID 0000-0002-2560-4631
Lauren TerhorstNational Rehabilitation Research and Training Center on Family Support, Health Policy Institute, University of Pittsburgh, Pittsburgh, PA, USA.
Juleen RodakowskiNational Rehabilitation Research and Training Center on Family Support, Health Policy Institute, University of Pittsburgh, Pittsburgh, PA, USA.
University of Pittsburgh · US

Funding

The National Health and Trends StudyU01AG032947 · NIA · JOHNS HOPKINS UNIVERSITY · PI VICKI A. FREEDMAN, JENNIFER ANN SCHRACK · 2008 to 2026
$169.4M
INFLUENCE OF STRATEGY TRAINING ON DISABILITY FOR OLDER ADULTS WITH MILD COGNITIVE IMPAIRMENTR01AG056351 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI RODAKOWSKI, JULEEN · 2019 to 2023
$3.2M
NIA NIH HHS R01 AG056351NIA NIH HHS U01 AG032947
6 · The paper itself

Abstract

objectiveInstrumental activities of daily living (IADL) are important for managing multiple chronic conditions (MCC) and maintaining independence while aging. Using data from the National Health and Aging Trends Study (NHATS), we answered the question: are there differences in ability and performance of IADL among groups of older adults with 0-1 (no MCC), 2-4 (low MCC), and 5+ chronic conditions (multisystem morbidity: MM)?

methodsCross-sectional study using Poisson regression and incidence rate ratios. Participants were 6,019 community-dwelling older adults who regularly take medications. We derived composite variables for ability and performance of IADL; MCC groups were based on count of 11 chronic conditions.

resultsOlder adults with MM had lower IADL count for ability (IRR = .81) and performance (IRR = .77), and MM group significantly predicted both ability and performance of IADL (p < .001); 'low MCC' group was not significantly different than 'no MCC' regarding disability. DISCUSSION: Having MM is statistically and clinically different than having low MCC or no MCC; 5+ chronic conditions may be a meaningful inclusion criterion for interventions to decrease disability and 2-4 chronic conditions may be better for trials to prevent disability. Researchers should measure both ability and performance of daily activity.

Indexed as

Activities of Daily LivingMultiple Chronic ConditionsAgedChronic DiseaseCross-Sectional StudiesHumansIndependent LivingMultimorbiditydaily activitydisabilityinstrumental activities of daily livingMultimorbiditymultiple chronic conditions

Identifiers

PMID34159840
PMCPMC8695626
OpenAlexW3175611492

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.