Evidence map›Paper›PMID 34159743›Full record

ArticleJournal of medical radiation sciences2021

Renal stone detection using a low kilo-voltage paediatric CT protocol - a porcine phantom study.

Bo Mussmann, Maryann Hardy, Helene Jung, Ming Ding, Palle J Osther, Maja Lynge Fransen, Pernille Wied Greisen, Ole Graumann

Open access · goldAbstract read
In one paragraph

Article in Journal of medical radiation sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Bo MussmannDepartment of Radiology, Odense University Hospital, Odense, Denmark.ORCID https://orcid.org/0000-0003-2119-5129
Maryann HardyResearch and Innovation Unit of Radiology, University of Southern Denmark, Odense, Denmark.
Helene JungUrological Research Center, Department of Urology, Lillebaelt Hospital, Vejle, Denmark.
Ming DingDepartment of Orthopaedic surgery and traumatology, Odense University Hospital, Odense, Denmark.
Palle J OstherUrological Research Center, Department of Urology, Lillebaelt Hospital, Vejle, Denmark.
Maja Lynge FransenDepartment of Radiology, Odense University Hospital, Odense, Denmark.
Pernille Wied GreisenDepartment of Radiology, Odense University Hospital, Odense, Denmark.
Ole GraumannDepartment of Radiology, Odense University Hospital, Odense, Denmark.
University of Southern Denmark · DKOdense University Hospital · DKUniversity of Bradford · GB

Funding

International Society of Radiographers and Radiological Technologists (ISRRT)
6 · The paper itself

Abstract

introductionReducing tube voltage is an effective dose saving method in computed tomography (CT) assuming tube current is not concurrently increased. Recent innovations in scanner technology now enable CT tube voltage reduction to 70 kV thereby increasing opportunities for dose reduction in paediatric patients, but it is unclear if the increased image noise associated with 70 kV impacts on ability to visualise renal stones accurately. The purpose was to assess detectability of nephrolithiasis using a bespoke paediatric phantom and low kV, non-contrast CT and to assess inter-observer agreement.

methodsForty-two renal stones of different size and chemical composition were inserted into porcine kidneys and positioned in a bespoke, water-filled phantom mimicking a 9-year-old child weighing approximately 33kg. The phantom was scanned using 120 and 70 kV CT protocols, and the detectability of the stones was assessed by three radiologists. Absolute agreement and Fleiss' kappa regarding detectability were assessed.

resultsThe mean diameter of renal stones as measured physically was 4.24 mm ranging from 1 to 11 mm. Four stones were missed by at least one observer. One observer had a sensitivity of 93 and 95% at 70 and 120 kV, respectively, while the sensitivity for observers 2 and 3 was 98% at both kV levels. Specificity was 100% across readers and kV levels. Absolute agreement between the readers at 70 kV was 92% (kappa = 0.86) and 98% (kappa = 0.96) at 120 kV indicating a strong agreement at both kV levels.

conclusionsThe results suggest that lowering the kV does not affect the detection rate of renal stones and may be a useful dose reduction strategy for assessment of nephrolithiasis in children.

Indexed as

Tomography, X-Ray ComputedAnimalsChildHumansPhantoms, ImagingRadiation DosageSwinecomputed tomographydetectiondose reductionimage noiseobserver performanceoptimization

Identifiers

PMID34159743
PMCPMC8656188
OpenAlexW3175303852

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.