Evidence map›Paper›PMID 34159571›Full record

ReviewReproductive sciences (Thousand Oaks, Calif.)2022

The Search for Biomarkers in Endometriosis: a Long and Windy Road.

Milena Králíčková, Vaclav Vetvicka, Luděk Fiala, Antonio Simone Laganà, Simone Garzon

Abstract readReview
PubMed Publisher
In one paragraph

Review in Reproductive sciences (Thousand Oaks, Calif.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. A Systematic Review of Atypical Endometriosis-Associated Biomarkers.International journal of molecular sciences · 2022
    Pooled it
  2. Article
  3. Review
  4. Article
  5. Molecular Biology of Human Fertility: Stepping towards a Tailored Approach.International journal of molecular sciences · 2022
    Article
  6. Review
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Milena KrálíčkováDepartment of Histology and Embryology, Faculty of Medicine, Charles University, Pilsen, Czech Republic.ORCID 0000-0003-1907-4774
Vaclav VetvickaDepartment of Pathology, University of Louisville, Louisville, KY, USA.ORCID 0000-0002-3227-2938
Luděk FialaInstitute of Sexology, First Faculty of Medicine, Charles University, Prague, Czech Republic.ORCID 0000-0001-6582-3014
Antonio Simone LaganàDepartment of Obstetrics and Gynecology, "Filippo Del Ponte" Hospital, University of Insubria, Piazza Biroldi 1, 21100, Varese, Italy. antoniosimone.lagana@uninsubria.it.ORCID 0000-0003-1543-2802
Simone GarzonDepartment of Obstetrics and Gynecology, "Filippo Del Ponte" Hospital, University of Insubria, Piazza Biroldi 1, 21100, Varese, Italy.ORCID 0000-0002-5840-699X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endometriosis is a complex and chronic estrogen-dependent disease, affecting a significant proportion of women of reproductive age. Despite the long interest and extensive research, the pathogenesis of the disease is still debated. Although available non-invasive diagnostic methods have adequate accuracy, an invasive approach by laparoscopy is often necessary to obtain histological confirmation. In this scenario, the search for an accurate, reliable, cost-effective, clinically applicable non-invasive biomarker plays a crucial role in a potentially early diagnosis and, in this way, shape the future management of the disease. Considering these elements, the current review aims to summarize the most significant and novel results about biomarkers for the diagnosis and follow-up of women affected by endometriosis.

Indexed as

EndometriosisBiomarkersFemaleHumansBiomarkersBiomarkerCA-125EndometriosisHuman epididymis protein 4ImmunologyMicroRNAStem cells

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.