ArticleEuropean radiology experimental2021
Quantitative benchmarking of iodine imaging for two CT spectral imaging technologies: a phantom study.
Article in European radiology experimental, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed, 25 citations in OpenAlex.
- Accurate iodine quantification and residual error reduction with principal component analysis multimaterial decomposition using spectral CT.Medical physics · 2026Article
- The value of dual-energy spectral CT in differentiating the pathological grades of T1-size lung adenocarcinoma.Journal of thoracic disease · 2025Article
- Spectral Differentiation of Hyperdense Non-Vascular and Vascular Renal Lesions Without Solid Components in Contrast-Enhanced Photon-Counting Detector CT Scans-A Pilot Study.Diagnostics (Basel, Switzerland) · 2025Article
- Creating a Foundation for the Visualization of Intracranial Cerebrospinal Fluid Using Photon-Counting Technology in Spectral Imaging for Cranial CT.Diagnostics (Basel, Switzerland) · 2024Article
- Estimation of renal function using iodine maps in dual-energy spectral computed tomography urography: a feasibility and accuracy study.Abdominal radiology (New York) · 2024Article
- Dual-Energy CT Iodine Uptake of Head and Neck: Definition of Reference Values in a Big Data Cohort.Diagnostics (Basel, Switzerland) · 2024Article
- Virtual unenhanced dual-energy computed tomography for photon radiotherapy: The effect on dose distribution and cone-beam computed tomography based position verification.Physics and imaging in radiation oncology · 2024Article
- Quantifying iodine concentration in the normal bowel wall using dual-energy CT: influence of patient and contrast characteristics.Scientific reports · 2023Article
- Determining the Optimal Energy Level of Virtual Monoenergetic Images in Dual-Source CT for Diagnosis of Bowel Obstruction and Colitis.Diagnostics (Basel, Switzerland) · 2023Article
- Quantitative performance of photon-counting CT at low dose: Virtual monochromatic imaging and iodine quantification.Medical physics · 2023Article
- Terbium-doped carbon dots (Tb-CDs) as a novel contrast agent for efficient X-ray attenuation.RSC advances · 2023Article
- Comparison of image quality of two versions of deep-learning image reconstruction algorithm on a rapid kV-switching CT: a phantom study.European radiology experimental · 2023Article
- Diagnostic Effectiveness of Dual Source Dual Energy Computed Tomography for Benign and Malignant Thyroid Nodules.Evidence-based complementary and alternative medicine : eCAM · 2022Article
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4 authors at 2 institutions in 2 countries.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundThe aim of this study was to quantitatively benchmark iodine imaging across specific virtual monoenergetic energy levels, iodine maps and virtual non-contrast images with different phantom sizes and iodine concentrations, using a rapid switching dual-energy CT (DECT) and a dual source DECT, in order to investigate accuracy and potential differences between the technologies.
methodsSolutions of iodine contrast (10, 20, 30, 50, and 100 mg/mL), sterile water and saline were scanned in a phantom on a rapid switching single-source and dual-source DECT scanners from two different vendors. The phantom was equipped with polyurethane rings simulating three body sizes. The datasets were reconstructed in virtual monoenergetic energy levels (70, 80, 90, 100, 110, 120, 130, and 140 keV), virtual non-contrast images and iodine maps. HU and iodine concentrations were measured by placing ROIs in the iodine solutions.
resultsThe iodine concentrations were reproduced with a high degree of accuracy for the single-source DECT (1.8-9.0%), showing a slight dependence on phantom size. The dual source DECT technique showed deviant values (error -33.8 to 12.0%) for high concentrations. In relation to the virtual non-contrast measurements, the images from both vendors were affected by the iodine concentration and phantom size (-127.8 to 539.1 HU). Phantom size did not affect the calculated monoenergetic attenuation values, but the attenuation values varied between the scanners.
conclusionsQuantitative measurements of post-processed images are dependent on the concentration of iodine, the phantom size and different technologies. However, our study indicates that the iodine maps are reliable for quantification of iodine.
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