Evidence map›Paper›PMID 34159473›Full record

ArticleBreast cancer research and treatment2021

Developing patient-centred strategies to optimize the management of vasomotor symptoms in breast cancer patients: a survey of health care providers.

Katherine Marie Cole, Mark Clemons, Meshari Alzahrani, Gail Larocque, Fiona MacDonald, Lisa Vandermeer, Brian Hutton, Ardelle Piper, Greg Pond, Sharon McGee

Registry-linked trialOpen access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Breast cancer research and treatment, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05222464 (Utilizing MyChart to Assess the Effectiveness of Interventions for Vasomotor Symptoms), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05222464 phase4completednot on this mapstarted 2022, after this paper: background citation

Utilizing MyChart to Assess the Effectiveness of Interventions for Vasomotor Symptoms: A Feasibility Study (REaCT-Hot Flashes Pilot)

TypeinterventionalSponsorOttawa Hospital Research InstituteRan2022 to 2022Enrolled56ConditionsBreast CancerArmsStandard of care treatments
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Trial
  2. Vasomotor symptoms in early breast cancer-a "real world" exploration of the patient experience.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Katherine Marie ColeDivision of Medical Oncology, Department of Medicine, The University of Ottawa, 501 Smyth Road, Ottawa, ON, K1H 8L6, Canada.
Mark ClemonsDivision of Medical Oncology, Department of Medicine, The University of Ottawa, 501 Smyth Road, Ottawa, ON, K1H 8L6, Canada.
Meshari AlzahraniDivision of Medical Oncology, Department of Medicine, The University of Ottawa, 501 Smyth Road, Ottawa, ON, K1H 8L6, Canada.
Gail LarocqueThe Ottawa Hospital Cancer Centre, Ottawa, ON, Canada.
Fiona MacDonaldThe Ottawa Hospital Cancer Centre, Ottawa, ON, Canada.
Lisa VandermeerCancer Therapeutics Program, The Ottawa Hospital Research Institute, Ottawa, ON, Canada.
Brian HuttonClinical Epidemiology Program, The Ottawa Hospital Research Institute, Ottawa Ontario, Canada.
Ardelle PiperUniversity of Ottawa Health Services, Ottawa Ontario, Canada.
Greg PondDepartment of Oncology, McMaster University, Hamilton, ON, Canada.
Sharon McGeeDivision of Medical Oncology, Department of Medicine, The University of Ottawa, 501 Smyth Road, Ottawa, ON, K1H 8L6, Canada. shmcgee@toh.ca.ORCID http://orcid.org/0000-0002-0323-6372
Ottawa Hospital · CAUniversity of Ottawa · CAMcMaster University · CAOntario Institute for Cancer Research · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeVasomotor symptoms (VMS) such as hot flashes and night sweats are common in breast cancer patients and can affect both quality of life and treatment adherence. However, there is limited practical data to guide clinicians in the optimal selection of therapeutic strategies. A survey of health care providers was performed to better understand perspectives and prescribing practices for managing this problem.

methodsCanadian health care providers who treat patients with early stage breast cancer (EBC) participated in an anonymous electronic survey. Participants provided their perspectives on the prevalence and severity of VMS among patients with EBC, outlined their management strategies, and provided feedback on the perceived efficacy of interventions for VMS.

resultsResponses were received from 65 providers including breast oncologists (36/65, 55%) and nurses with oncology expertise (29/65, 45%). Seventy-seven percent of participants reported regularly asking patients about VMS, and most indicated that bothersome VMS occurred in the majority of patients. Health care providers cited hot flash severity and sleep disruption as the most important issues for patients. The most common first- and second-line interventions recommended were lifestyle modifications (n = 32/65, 49.2%) and pharmacologic strategies (n = 27/65, 41.5%), respectively. Most respondents felt that interventions, including pharmacologic, over-the-counter, and complementary therapies, were only "somewhat effective". Overall, half of respondents (n = 35/65, 54%) reported being "confident" in managing VMS.

conclusionGiven the variability of treatment recommendations, and health care provider uncertainty around the benefits of therapies for VMS, more 'real-world' trials are needed to optimize patient care.

Indexed as

Breast NeoplasmsMenopauseCanadaFemaleHealth PersonnelHot FlashesHumansQuality of LifeSurveys and QuestionnairesSweatingBreast cancerHot flashesSurvivorshipVasomotor symptoms

Identifiers

PMID34159473
PMCPMC8219176
OpenAlexW3174437576

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.