Evidence map›Paper›PMID 34159388›Full record

ArticleThe Journal of nutrition2021

Relation Between Body Composition, Systemic Inflammatory Response, and Clinical Outcomes in Patients Admitted to an Urban Teaching Hospital with COVID-19.

Josh McGovern, Ross Dolan, Conor Richards, Barry J Laird, Donald C McMillan, Donogh Maguire

Open access · hybridAbstract read
In one paragraph

Article in The Journal of nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 5 pooled it
2.0field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 5 syntheses or guidelines pooled it, 33 citations in OpenAlex.

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  12. Sarcopenia and COVID-19 Outcomes.Clinical interventions in aging · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Josh McGovernAcademic Unit of Surgery, School of Medicine, University of Glasgow, New Lister Building, Royal Infirmary, Glasgow, United Kingdom.
Ross DolanAcademic Unit of Surgery, School of Medicine, University of Glasgow, New Lister Building, Royal Infirmary, Glasgow, United Kingdom.
Conor RichardsSchool of Medicine, University of Glasgow, Glasgow, United Kingdom.
Barry J LairdInstitute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom.
Donald C McMillanAcademic Unit of Surgery, School of Medicine, University of Glasgow, New Lister Building, Royal Infirmary, Glasgow, United Kingdom.ORCID 0000-0003-4260-5334
Donogh MaguireEmergency Department, Glasgow Royal Infirmary, Glasgow, United Kingdom.
Glasgow Royal Infirmary · GBInstitute of Genetics and Cancer · GBUniversity of Glasgow · GB

Funding

Marie Curie MCRGS-07-16-73
6 · The paper itself

Abstract

backgroundCOVID-19 has been associated with cases of severe respiratory illness, admissions to intensive therapy units (ITUs), and high mortality rates.

objectivesThe aim of the present study was to examine the relation between computed tomography- body composition (CT-BC) measurements, systemic inflammation, and clinical outcomes in those with COVID-19.

methodsPatients who presented to our institution between March 17 and May 1, 2020, with a positive PCR test for COVID-19 or characteristic radiological changes, were assessed for inclusion. Data collected included general demographic details, clinicopathological variables, poGPS, NLR , CT-BC measurements, and clinical outcomes including ITU admission and 30-d mortality, of those admitted.

resultsSixty-three patients met the study inclusion criteria. Forty-two patients (67%) were aged ≥70 y, 30 (47.6%) were male and 34.9% ( n = 22) had a poGPS ≥1. ITU admission was significantly associated with a high VFA ( P < 0.05). Thirty-day mortality was associated with high VFA (P < 0.05) and low SMI (P < 0.05).

conclusionsSarcopenia in the presence of obesity was associated with clinical outcomes including greater 30-d mortality.

Indexed as

Body CompositionSARS-CoV-2AdultAgedAged, 80 and overBody Mass IndexCOVID-19FemaleHospitalizationHospitals, TeachingHumansInflammationIntra-Abdominal FatMaleMiddle AgedSarcopeniabody compositionCOVID-19CTobesitysarcopenia

Identifiers

PMID34159388
PMCPMC8195217
OpenAlexW3171291154

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.