Evidence map›Paper›PMID 34159293›Full record

ArticleTherapeutic advances in vaccines and immunotherapy2021

Generating CAR T cells from tumor-infiltrating lymphocytes.

Jane K Mills, Melissa A Henderson, Lauren Giuffrida, Pasquale Petrone, Jennifer A Westwood, Phillip K Darcy, Paul J Neeson, Michael H Kershaw, David E Gyorki

Open access · diamondAbstract read
In one paragraph

Article in Therapeutic advances in vaccines and immunotherapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
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  5. CAR-mediated target recognition limits TCR-mediated target recognition of TCR- and CAR-dual-receptor-edited T cells.Molecular therapy : the journal of the American Society of Gene Therapy · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Jane K MillsCancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne, Australia.
Melissa A HendersonCancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne, Australia.
Lauren GiuffridaCancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne, Australia.
Pasquale PetroneCancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne, Australia.
Jennifer A WestwoodCancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne, Australia.
Phillip K DarcyCancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne, Australia.
Paul J NeesonCancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne, Australia.
Michael H KershawCancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne, Australia.ORCID https://orcid.org/0000-0002-2697-487X
David E GyorkiDepartment of Cancer Surgery, Peter MacCallum Cancer Centre, 305 Grattan Street, Melbourne, Victoria 3000, Australia.
Peter MacCallum Cancer Centre · AUThe University of Melbourne · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

autologous tumorchimeric antigen receptorHer2immunotherapymelanoma

Identifiers

PMID34159293
PMCPMC8186112
OpenAlexW3172475403

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.