Evidence map›Paper›PMID 34159286›Full record

ArticleJournal of the Endocrine Society2021

Percutaneous Ultrasound-Guided Laser Ablation of Benign Thyroid Nodules: Results of 10-Year Follow-Up in 171 Patients.

Giovanni Gambelunghe, Elisa Stefanetti, Nicola Avenia, Pierpaolo De Feo

Open access · goldAbstract read
In one paragraph

Article in Journal of the Endocrine Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.

  1. Pooled it
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  3. Review
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  8. Review
  9. Review
  10. Laser Ablation for Benign and Malignant Thyroid Nodules - A Mini-Literature Review.Endocrine, metabolic & immune disorders drug targets · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Giovanni GambelungheEndocrine Unit, Clinica Liotti, 06123 Perugia, Italy.ORCID https://orcid.org/0000-0002-7149-4867
Elisa StefanettiStudio Tiroide Prof. De Feo, 06132 Perugia, Italy.
Nicola AveniaDepartment of Endocrine Surgery, Azienda Ospedaliero-Universitaria di Terni, 05100 Terni, Italy.
Pierpaolo De FeoEndocrine Unit, Clinica Liotti, 06123 Perugia, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextPercutaneous, ultrasound-guided laser ablation is effective in nodular thyroid disease.

objectiveThe aim of this study was to evaluate the long-term (10-year) efficacy and safety of laser ablation in the treatment of benign thyroid nodules.

methodsFrom 2009 to 2010, 171 patients received a single session of laser ablation. Evaluation of nodule volume was performed before treatment, at 6 months, and every year.

resultsTechnique efficacy was achieved in 92% of patients at 1 year. Median nodule volume significantly decreased from 16.7 mL (range, 11.0-97.0 mL) at baseline to 5.0 mL (range, 4.1-32.0 mL) at 1 year, a volume reduction ratio (VRR) of 68%. The benefit of the treatment was durable (

conclusionPercutaneous, ultrasound-guided laser ablation of benign thyroid nodules provides long-term benefits and the treatment is well tolerated.

Indexed as

benign nodulesEchoLaserfollow-upModìLitepercutaneous laser ablation

Identifiers

PMID34159286
PMCPMC8212682
OpenAlexW3160968524

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.