Evidence map›Paper›PMID 34159251›Full record

ArticleInternational journal of cardiology. Heart & vasculature2021

Clinical effectiveness of a dedicated cardiac resynchronization therapy pre-assessment clinic incorporating cardiac magnetic resonance imaging and cardiopulmonary exercise testing on patient selection and outcomes.

Baldeep S Sidhu, Justin Gould, Mark K Elliott, Vishal S Mehta, Steven A Niederer, Gerald Carr-White, Christopher A Rinaldi

Open access · goldAbstract read
In one paragraph

Article in International journal of cardiology. Heart & vasculature, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Baldeep S SidhuSchool of Biomedical Engineering and Imaging Sciences, King's College London, UK.
Justin GouldSchool of Biomedical Engineering and Imaging Sciences, King's College London, UK.
Mark K ElliottSchool of Biomedical Engineering and Imaging Sciences, King's College London, UK.
Vishal S MehtaSchool of Biomedical Engineering and Imaging Sciences, King's College London, UK.
Steven A NiedererSchool of Biomedical Engineering and Imaging Sciences, King's College London, UK.
Gerald Carr-WhiteSchool of Biomedical Engineering and Imaging Sciences, King's College London, UK.
Christopher A RinaldiSchool of Biomedical Engineering and Imaging Sciences, King's College London, UK.
St Thomas' Hospital · GBKing's College London · GB

Funding

Wellcome Trust 203148/Z/16/Z
6 · The paper itself

Abstract

backgroundPre-procedural assessment of patients undergoing cardiac resynchronization therapy (CRT) is heterogenous and patients implanted with unfavorable characteristics may account for non-response. A dedicated CRT pre-assessment clinic (CRT PAC) was developed to standardize the review process and undertake structured pre-procedural evaluation. The aim of this analysis was to determine the effectiveness on patient selection and outcomes.

methodsA prospective database of consecutive patients attending the CRT PAC between 2013 and 2018 was analyzed. Pre-operative assessment included cardiac magnetic resonance (CMR) and cardiopulmonary exercise testing (CPET). Patients were considered CRT responders based on improvement in clinical composite score (CCS) and/or reduction in left ventricular end-systolic volume (LVESV) ≥ 15% at 6-months follow-up.

resultsOf 252 patients reviewed in the CRT PAC during the analysis period, 192 fulfilled consensus guidelines for implantation. Of the patients receiving CRT, 82% showed improvement in their CCS and 57% had a reduction in LVESV ≥ 15%. The presence of subendocardial scar on CMR and a peak VO

conclusionA dedicated CRT PAC is able to appropriately select patients for CRT. Pre-procedural investigation/imaging can identify patients unlikely to respond to, or may not yet be suitable for CRT.

Indexed as

Cardiac magnetic resonance imagingCardiac resynchronization therapyCardiopulmonary exercise testingHeart failure

Identifiers

PMID34159251
PMCPMC8203725
OpenAlexW3172630806

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.