Evidence map›Paper›PMID 34159217›Full record

ArticleOpen forum infectious diseases2021

The Relationship Between Hepatitis C Virus Rates and Office-Based Buprenorphine Access in Ohio.

Daniel L Brook, Angela T Hetrick, Shibani R Chettri, Christine A Schalkoff, Adams L Sibley, Kathryn E Lancaster, Vivian F Go, William C Miller, David M Kline

Abstract read
In one paragraph

Article in Open forum infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Daniel L BrookDivision of Epidemiology, The Ohio State University College of Public Health, Columbus, Ohio, USA.ORCID https://orcid.org/0000-0003-4772-2986
Angela T HetrickDivision of Epidemiology, The Ohio State University College of Public Health, Columbus, Ohio, USA.
Shibani R ChettriDivision of Epidemiology, The Ohio State University College of Public Health, Columbus, Ohio, USA.
Christine A SchalkoffDepartment of Health Behavior, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Adams L SibleyDepartment of Health Behavior, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Kathryn E LancasterDivision of Epidemiology, The Ohio State University College of Public Health, Columbus, Ohio, USA.
Vivian F GoDepartment of Health Behavior, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
William C MillerDivision of Epidemiology, The Ohio State University College of Public Health, Columbus, Ohio, USA.
David M KlineCenter for Biostatistics, Department of Biomedical Informatics, The Ohio State University College of Medicine, Columbus, Ohio, USA.

Funding

Implementing a Community-Based Response to the Opioid Epidemic in Rural OhioUG3DA044822 · NIDA · OHIO STATE UNIVERSITY · PI GO, VIVIAN F., MILLER, WILLIAM C · 2017 to 2018
$1.1M
The role of injection partnerships and preferences for reducing HCV risk: Giving a voice to young women in rural Appalachia.K01DA048174 · NIDA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI LANCASTER, KATHRYN ELIZABETH · 2019 to 2023
$841k
Buprenorphine, Hepatitis C Virus and Their Relationship in Rural US PopulationsF30DA050423 · NIDA · OHIO STATE UNIVERSITY · PI BROOK, DANIEL · 2020 to 2023
$184k
NIDA NIH HHS F30 DA050423NIDA NIH HHS K01 DA048174NIDA NIH HHS UG3 DA044822
6 · The paper itself

Abstract

backgroundThe United States is experiencing an epidemic of hepatitis C virus (HCV) infections due to injection drug use, primarily of opioids and predominantly in rural areas. Buprenorphine, a medication for opioid use disorder, may indirectly prevent HCV transmission. We assessed the relationship of HCV rates and office-based buprenorphine prescribing in Ohio.

methodsWe conducted an ecological study of the county-level (n = 88) relationship between HCV case rates and office-based buprenorphine prescribing in Ohio. We fit adjusted negative binomial models between the county-level acute and total HCV incidence rates during 2013-2017 and 1) the number of patients in each county that could be served by office-based buprenorphine (

resultsFor each 10% increase in acute HCV rate, office-based buprenorphine prescribing capacity differed by 1% (95% CI: -1%, 3%). For each 10% increase in total HCV rate, office-based buprenorphine prescribing capacity was 12% (95% CI: 7%, 17%) higher. For each 10% increase in acute HCV rate, office-based buprenorphine prescribing frequency was 1% (95% CI: -1%, 3%) higher. For each 10% increase in total HCV rate, office-based buprenorphine prescribing frequency was 14% (95% CI: 7%, 20%) higher.

conclusionsRural counties in Ohio have less office-based buprenorphine and higher acute HCV rates versus urban counties, but a similar relationship between office-based buprenorphine prescribing and HCV case rates. To adequately prevent and control HCV rates, certain rural counties may need more office-based buprenorphine prescribing in areas with high HCV case rates.

Indexed as

buprenorphineHCVOhioopioids

Identifiers

PMID34159217
PMCPMC8214012

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.