Evidence map›Paper›PMID 34159068›Full record

ArticlePublic health action2021

Caregivers' knowledge and perceptions are associated with children's TB preventive treatment completion.

J Zeladita-Huaman, C M Yuen, R Zegarra-Chapoñan, M Curisinche-Rojas, V Egusquiza-Pozo

Open access · diamondAbstract read
In one paragraph

Article in Public health action, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

J Zeladita-HuamanUniversidad Nacional Mayor de San Marcos, Facultad de Medicina, Lima, Peru.
C M YuenHarvard Medical School, Department of Global Health and Social Medicine, Boston, MA, USA.
R Zegarra-ChapoñanUniversidad Maria Auxiliadora, Facultad de Ciencias de la Salud, Lima, Peru.
M Curisinche-RojasUniversidad Cientifica del Sur, School of Nursing, Lima, Peru.
V Egusquiza-PozoUniversidad Maria Auxiliadora, Facultad de Ciencias de la Salud, Lima, Peru.
Universidad María AuxiliadoraHarvard University · USNational University of San Marcos · PEUniversidad Científica del Sur · PE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

settingForty-six health centers in south Lima, Peru.

objectiveTo assess the association between caregivers' knowledge and perceptions around isoniazid preventive therapy (IPT) and whether their children complete IPT.

designWe conducted a retrospective medical record review of children who initiated IPT during 2017-2018. We administered structured surveys to caregivers of the children about their knowledge about and perceptions of IPT. We used a modified Poisson regression to determine factors associated with IPT completion.

resultsWe included 550 children, of whom 31% did not complete IPT. Independent factors associated with not completing IPT were low caregiver knowledge about TB and IPT (adjusted risk ratio [aRR] 1.41, 95% CI 1.06-1.78), low caregiver perception of the importance of IPT (aRR 1.76, 95% CI 1.30-2.39), low caregiver satisfaction with the health services (aRR 1.57, 95% CI 1.14-2.16), experience of adverse events (aRR 2.08, 95% CI 1.51-2.87), and living in a household with moderate or severe family dysfunction (aRR 1.53, 95% CI 1.07-2.19).

conclusionIPT completion among children was associated with the knowledge and perceptions of their caregivers, as well as the experience of adverse events. To improve IPT completion among children, health care providers should prioritize education and counseling for caregivers, promote positive interpersonal relationships with them, and monitor adverse events.

Indexed as

adolescentschildrenisoniazidpreventive therapytuberculosis

Identifiers

PMID34159068
PMCPMC8202630
OpenAlexW3171434178

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.