Evidence map›Paper›PMID 34159060›Full record

ArticlePublic health action2021

Experiences of introducing new drugs for drug-resistant TB at the ALERT Hospital, Addis Ababa, Ethiopia, 2017-2019.

E Tesema, F Wares, A Bedru, C Negeri, Y Molla, D Gemechu, A Kassa, F Tsegaye, L Taye

Abstract read
In one paragraph

Article in Public health action, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

E TesemaChallenge TB/KNCV TB Foundation, Addis Ababa, Ethiopia.
F WaresChallenge TB/KNCV TB Foundation, The Hague, The Netherlands.
A BedruChallenge TB/KNCV TB Foundation, Addis Ababa, Ethiopia.
C NegeriChallenge TB/KNCV TB Foundation, Addis Ababa, Ethiopia.
Y MollaChallenge TB/KNCV TB Foundation, Addis Ababa, Ethiopia.
D GemechuChallenge TB/MSH, Addis Ababa, Ethiopia.
A KassaABT Associates, Federal Ministry of Health, Addis Ababa, Ethiopia.
F TsegayeALERT Hospital, Addis Ababa, Ethiopia.
L TayeNational TB Programme, Federal Ministry of Health, Addis Ababa, Ethiopia.

Funding

Ethiopia-Emory TB Research Training ProgramD43TW009127 · FIC · EMORY UNIVERSITY · PI HENRY M BLUMBERG, Kidist Bobosha · 2013 to 2026
$3.4M
FIC NIH HHS D43 TW009127
6 · The paper itself

Abstract

backgroundDrug-resistant TB (DR-TB) remains a major public health concern. DR-TB patient data from ALERT (All Africa Leprosy, Tuberculosis and Rehabilitation Training Centre) Hospital, Addis Ababa, Ethiopia, who received bedaquiline (BDQ) and/or delamanid (DLM) containing regimens were analysed.

resultsFrom 2017 to 2019, 51 DR-TB patients were enrolled. Of 33 patients, 31 (93.9%) had culture converted at 6 months. Of those with final outcomes, 77% (

conclusionWith close monitoring, introduction of new DR-TB regimens brought good early results, which encouraged wider programmatic implementation in Ethiopia.

Indexed as

adverse event, treatment outcomeALERT Hospitalmultidrug-resistant-TB

Identifiers

PMID34159060
PMCPMC8202633

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.