Evidence map›Paper›PMID 34158953›Full record

ArticleOxford medical case reports2021

Varicella-zoster virus aseptic meningitis: an atypical presentation in an immunocompetent male patient.

Christina Platanaki, Leonidia Leonidou, Dimitrios Siagkris, Ιoanna Giannopoulou, Fotini Paliogianni, Dimitrios Velissaris

Open access · goldAbstract readCase Reports
In one paragraph

Article in Oxford medical case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Christina PlatanakiDepartment of Internal Medicine, University General Hospital of Patras, Patras, Greece.
Leonidia LeonidouDepartment of Internal Medicine, University General Hospital of Patras, Patras, Greece.
Dimitrios SiagkrisDepartment of Internal Medicine, University General Hospital of Patras, Patras, Greece.
Ιoanna GiannopoulouDepartment of Microbiology, University General Hospital of Patras, Patras, Greece.
Fotini PaliogianniDepartment of Microbiology, University General Hospital of Patras, Patras, Greece.
Dimitrios VelissarisDepartment of Internal Medicine, University General Hospital of Patras, Patras, Greece.
General University Hospital of Patras · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Varicella-zoster virus (VZV) reactivation causes a relatively common disease in immunocompromised patients characterized by rash and radiating pain. Aseptic meningitis is a rare complication of VZV infection and commonly is associated with exanthem and neurological signs. We present an atypical case of VZV meningitis in a healthy 56-year-old male who was initially presented with persistent headache as the only symptom. Anti-VZV immunoglobulin G titer both in serum and in cerebrospinal fluid (CSF) and the polymerase chain reaction (PCR) CSF analysis revealed VZV infection. Our case highlights the importance of considering VZV aseptic meningitis in immunocompetent individuals even in the absence of the typical presentation of meningitis. Screening techniques such as CSF, PCR as well as anti-VZV antibodies in CSF show that VZV meningitis is a common cause of aseptic meningitis and allows the early recognition of CNS involvement in the VZV infection.

Identifiers

PMID34158953
PMCPMC8212675
OpenAlexW3173665499

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.