Evidence map›Paper›PMID 34158866›Full record

ReviewTheranostics2021

Recent strategies for nano-based PTT combined with immunotherapy: from a biomaterial point of view.

Xingyue Huang, Yang Lu, Mingxue Guo, Shouying Du, Ning Han

Open access · goldAbstract readReview
In one paragraph

Review in Theranostics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 90 papers.

0numbers the graph read from it
0cells of the map it votes in
90citing papers in PubMed
13.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

90 citing papers in PubMed, 245 citations in OpenAlex.

  1. Review
  2. Article
  3. PEGylated Cu-doped WSMicrosystems & nanoengineering · 2026
    Article
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  5. Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Review
  11. Review
  12. Review
  13. Article
  14. Article
  15. Emerging Nanozyme Strategies for Precision Breast Cancer Treatment.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  16. Article
  17. Article
  18. Review
  19. Review
  20. Biomineralized engineeredJournal for immunotherapy of cancer · 2025
    Article

30 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Xingyue HuangSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, China.
Yang LuSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, China.
Mingxue GuoSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, China.
Shouying DuSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, China.
Ning HanSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, China.
Beijing University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer has been a great threat to humans for decades. Due to the limitations of monotherapy, combinational therapies such as photothermal therapy (PTT) and immunotherapy have gained increasing attention with expectation to overcome the shortfalls of each other and obtain satisfactory therapeutic outcomes. PTT can inhibit primary tumors by thermal ablation but usually fails to achieve complete eradication and cannot prevent metastasis and recurrence. Meanwhile, the efficacy of immunotherapy is usually attenuated by the weak immunogenicity of tumor and the immunosuppressive tumor microenvironment (ITM). Therefore, many recent studies have attempted to synergize PTT with immunotherapy in order to enhance the therapeutic efficacy. In this review, we aim to summarize the cutting-edge strategies in combining nano-based PTT with immunotherapy for cancer treatment. Herein, the combination strategies were mainly classified into four categories, including 1) nano-based PTT combined with antigens to induce host immune responses; 2) nano-based PTT in combination with immune adjuvants acting as

Indexed as

ImmunotherapyPhotothermal TherapyAdjuvants, ImmunologicBiocompatible MaterialsHumansNeoplasmsTumor MicroenvironmentAdjuvants, ImmunologicBiocompatible Materialscancercombination therapyimmunotherapynanoplatformsphotothermal therapy

Identifiers

PMID34158866
PMCPMC8210617
OpenAlexW3176085841

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.