Evidence map›Paper›PMID 34158854›Full record

ArticleTheranostics2021

HIF-1-induced mitochondrial ribosome protein L52: a mechanism for breast cancer cellular adaptation and metastatic initiation in response to hypoxia.

Xinyan Li, Mengshen Wang, Su Li, Yuqiong Chen, Mozhi Wang, Zhonghua Wu, Xiangyu Sun, Litong Yao, Haoran Dong, Yongxi Song and 1 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
3.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 60 citations in OpenAlex.

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  14. Multi-omic studies on the pathogenesis of Sepsis.Journal of translational medicine · 2025
    Article
  15. Article
  16. Mitochondrial Ribosomal Proteins and Cancer.Medicina (Kaunas, Lithuania) · 2025
    Review
  17. scFocus: Detecting branching probabilities in single-cell data with SAC.Computational and structural biotechnology journal · 2025
    Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Xinyan LiDepartment of Breast Surgery, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning, China.
Mengshen WangDepartment of Breast Surgery, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning, China.
Su LiDepartment of Cardiology, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China.
Yuqiong ChenDepartment of Cardiology, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning, China.
Mozhi WangDepartment of Breast Surgery, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning, China.
Zhonghua WuDepartment of Surgical Oncology and General Surgery, Key Laboratory of Precision Diagnosis and Treatment of Gastrointestinal Tumors, Ministry of Education, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning, China.
Xiangyu SunDepartment of Breast Surgery, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning, China.
Litong YaoDepartment of Breast Surgery, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning, China.
Haoran DongDepartment of Breast Surgery, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning, China.
Yongxi SongDepartment of Surgical Oncology and General Surgery, Key Laboratory of Precision Diagnosis and Treatment of Gastrointestinal Tumors, Ministry of Education, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning, China.
Yingying XuDepartment of Breast Surgery, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning, China.
First Hospital of China Medical University · CNChina Medical University · CNZhongshan Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Adaptation, PhysiologicalBreast NeoplasmsCell HypoxiaFemaleHumansHypoxia-Inducible Factor 1MCF-7 CellsMitochondrial ProteinsNeoplasm ProteinsRibosomal ProteinsHypoxia-Inducible Factor 1Mitochondrial ProteinsNeoplasm ProteinsRibosomal ProteinsBreast cancerHypoxiaMetastasisMitochondrial ribosomeMitophagy

Identifiers

PMID34158854
PMCPMC8210597
OpenAlexW3172823398

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.