ArticleTheranostics2021
EGFR-targeted intraoperative fluorescence imaging detects high-grade glioma with panitumumab-IRDye800 in a phase 1 clinical trial.
Open access · goldAbstract readClinical Trial, Phase IMulticenter Study
In one paragraph
Article in Theranostics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
5.4field-weighted citation impact, top 3% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 52 citations in OpenAlex.
- Interim Phase II Results Using Panitumumab-IRDye800CW during Transoral Robotic Surgery in Patients with Oropharyngeal Cancer.Clinical cancer research : an official journal of the American Association for Cancer Research · 2024Trial
- Fluorescent Molecular Imaging Can Improve Intraoperative Sentinel Margin Detection in Oral Squamous Cell Carcinoma.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2022Trial
- Clinical fluorescent probes: mechanisms, advantages and inspirations.Chemical science · 2026Review
- Imaging strategies for delineating glioma margins: Aiming at precise therapy.Fundamental research · 2026Review
- Use of Dual-Modality Antibody Imaging for Assessment of Lymph Node Metastases in Head and Neck Cancer.Theranostics · 2026Article
- Photosensitizer-Antibody Conjugates (PhotoBodies): Emerging Frontiers in the Field of Theranostics.Pharmaceutical research · 2026Review
- Evaluation of a near-infrared version of TMR-PEG1k, a high-performance untargeted contrast agent for fluorescence-guided surgery, using fluorescence cryotomography.Journal of biomedical optics · 2025Article
- Investigating the mechanisms of indocyanine green tumour uptake in sarcoma cell lines and ex vivo human tissue.The Journal of pathology · 2025Article
- Fluorescence molecular imaging of high-grade gliomas and brain metastases using the RAS70 peptide targeting plasma membrane-bound Hsp70 on tumor cells.Journal of neuro-oncology · 2025Article
- Brightening New Horizons: Luminescent Transition Metal Complexes in Optical Imaging and Theranostic Applications.ACS central science · 2025Review
- Review
- Review
- Elucidating the effect of tumor and background region-of-interest selection on the performance metrics used to assess fluorescence imaging.Journal of biomedical optics · 2025Article
- Visualization of Brain Tumors with Infrared-Labeled Aptamers for Fluorescence-Guided Surgery.Journal of the American Chemical Society · 2024Article
- Illuminating the future of precision cancer surgery with fluorescence imaging and artificial intelligence convergence.NPJ precision oncology · 2024Review
- Monoclonal Antibodies for Targeted Fluorescence-Guided Surgery: A Review of Applicability across Multiple Solid Tumors.Cancers · 2024Review
- Near-Infrared Fluorescence Imaging in Preclinical Models of Glioblastoma.Journal of imaging · 2023Article
- Investigating Effects of IR-780 in Animal Models of B16-F10 Melanoma: New Approach in Lung Metastasis.Molecules (Basel, Switzerland) · 2023Article
- Preclinical assessment of IRDye800CW-labeled gastrin-releasing peptide receptor-targeting peptide for near infrared-II imaging of brain malignancies.Bioengineering & translational medicine · 2023Article
- Rapid and Quantitative Intraoperative Pathology-Assisted Surgery by Paired-Agent Imaging-Derived Confidence Map.Molecular imaging and biology · 2023Article
Corrections and comments
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Authors and funding
24 authors at 1 institution in 1 country.
Quan ZhouDepartment of Neurosurgery, Stanford University School of Medicine, Stanford, CA, USA.
Nynke S van den BergOtolaryngology-Head and Neck Surgery, Stanford University School of Medicine, Stanford, CA, USA.
Eben L RosenthalOtolaryngology-Head and Neck Surgery, Stanford University School of Medicine, Stanford, CA, USA.
Michael IvDepartment of Radiology, Stanford University School of Medicine, Stanford, CA, USA.
Michael ZhangDepartment of Neurosurgery, Stanford University School of Medicine, Stanford, CA, USA.
Johana C M Vega LeonelDepartment of Neurosurgery, Stanford University School of Medicine, Stanford, CA, USA.
Shannon WaltersDepartment of Radiology, Stanford University School of Medicine, Stanford, CA, USA.
Naoki NishioOtolaryngology-Head and Neck Surgery, Stanford University School of Medicine, Stanford, CA, USA.
Monica GranucciCancer Clinical Trials Office, Stanford University School of Medicine, Stanford, CA, USA.
Roan RaymundoOtolaryngology-Head and Neck Surgery, Stanford University School of Medicine, Stanford, CA, USA.
Grace YiOtolaryngology-Head and Neck Surgery, Stanford University School of Medicine, Stanford, CA, USA.
Hannes VogelDepartment of Neuropathology, Stanford University School of Medicine, Stanford, CA, USA.
Romain CayrolDepartment of Neuropathology, Stanford University School of Medicine, Stanford, CA, USA.
Yu-Jin LeeOtolaryngology-Head and Neck Surgery, Stanford University School of Medicine, Stanford, CA, USA.
Guolan LuOtolaryngology-Head and Neck Surgery, Stanford University School of Medicine, Stanford, CA, USA.
Marisa HomOtolaryngology-Head and Neck Surgery, Stanford University School of Medicine, Stanford, CA, USA.
Wenying KangOtolaryngology-Head and Neck Surgery, Stanford University School of Medicine, Stanford, CA, USA.
Melanie Hayden GephartDepartment of Neurosurgery, Stanford University School of Medicine, Stanford, CA, USA.
Larry RechtDepartment of Neurology, Stanford University School of Medicine, Stanford, CA, USA.
Seema NagpalDepartment of Neurology, Stanford University School of Medicine, Stanford, CA, USA.
Reena ThomasDepartment of Neurology, Stanford University School of Medicine, Stanford, CA, USA.
Chirag PatelDepartment of Neurology, Stanford University School of Medicine, Stanford, CA, USA.
Gerald A GrantDepartment of Neurosurgery, Stanford University School of Medicine, Stanford, CA, USA.
Gordon LiDepartment of Neurosurgery, Stanford University School of Medicine, Stanford, CA, USA.
Stanford University · US
Funding
VECTOR COREP30NS069375 · NINDS · STANFORD UNIVERSITY · PI SHAMLOO, MEHRDAD · 2011 to 2019
$6.3MStanford Molecular Imaging Scholars (SMIS) ProgramT32CA118681 · NCI · STANFORD UNIVERSITY · PI CRAIG S LEVIN · 2016 to 2026
$4.3MOptical Imaging to Improve Surgery & Targeted Therapy in Brain TumorsR01CA239257 · NCI · STANFORD UNIVERSITY · PI LI, GORDON, ROSENTHAL, EBEN L. · 2019 to 2023
$2.9MPrototype optical device for image guided surgery with panitumumab-IRDye800R01CA190306 · NCI · STANFORD UNIVERSITY · PI ROSENTHAL, EBEN L. · 2015 to 2019
$2.6MClinician-scientist training program in otolaryngologyT32DC015209 · NIDCD · STANFORD UNIVERSITY · PI CHENG, ALAN GI-LUN · 2016 to 2021
$807kNCI NIH HHS R01 CA190306NCI NIH HHS R01 CA239257NCI NIH HHS T32 CA118681NIDCD NIH HHS T32 DC015209NINDS NIH HHS P30 NS069375
Abstract
PubMed holds no abstract for this paper.
Indexed as
Brain NeoplasmsDrug Delivery SystemsGliomaOptical ImagingAdultAgedDisease-Free SurvivalErbB ReceptorsFemaleHumansIndolesIntraoperative CareMaleMiddle AgedNeoplasm ProteinsPanitumumabEGFR protein, humanErbB ReceptorsIndolesIRDye800Neoplasm ProteinsPanitumumabepidermal growth factor receptorfluorescence imagingHigh-grade gliomapanitumumab-IRDye800phase 1
Identifiers
What OpenQuestion holds
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LicenceCC BY
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.