Evidence map›Paper›PMID 34158738›Full record

ArticleChinese journal of cancer research = Chung-kuo yen cheng yen chiu2021

Current status and future perspectives on neoadjuvant therapy in gastric cancer.

Sheng Ao, Yuchen Wang, Qingzhi Song, Yingjiang Ye, Guoqing Lyu

Abstract read
In one paragraph

Article in Chinese journal of cancer research = Chung-kuo yen cheng yen chiu, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. [Reflections on surgical management strategies for locally advanced gastric cancer after neoadjuvant immunotherapy].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
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  9. Current status and perspectives of conversion therapy for advanced gastric cancer.Chinese journal of cancer research = Chung-kuo yen cheng yen chiu · 2022
    Article
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  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sheng AoDepartment of Gastrointestinal Surgery, Peking University Shenzhen Hospital, Shenzhen 518000, China.
Yuchen WangDepartment of Gastrointestinal Surgery, Peking University Shenzhen Hospital, Shenzhen 518000, China.
Qingzhi SongDepartment of Gastrointestinal Surgery, Peking University Shenzhen Hospital, Shenzhen 518000, China.
Yingjiang YeDepartment of Gastrointestinal Surgery, Peking University People's Hospital, Beijing 100044, China.
Guoqing LyuDepartment of Gastrointestinal Surgery, Peking University Shenzhen Hospital, Shenzhen 518000, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastric cancer, with high morbidity and mortality rates, is one of the most heterogeneous tumors. Radical gastrectomy and postoperative chemotherapy are the standard treatments. However, the safety and efficacy of neoadjuvant therapy (NAT) need to be confirmed by many trials before implementation, creating a bottleneck in development. Although clinical benefits of NAT have been observed, a series of problems remain to be solved. Before therapy, more contributing factors should be offered for choice in the intended population and ideal regimens. Enhanced computed tomography (CT) scanning is usually applied to evaluate effectiveness according to Response Evaluation Criteria in Solid Tumors (RECIST), yet CT scanning results sometimes differ from pathological responses. After NAT, the appropriate time for surgery is still empirically defined. Our review aims to discuss the abovementioned issues regarding NAT for GC, including indications, selection of regimens, lesion assessment and NAT-surgery interval time.

Indexed as

Gastric cancerlesion assessmentNAT-surgery interval timeneoadjuvant therapyregimens

Identifiers

PMID34158738
PMCPMC8181872

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.