ArticleJournal of Indian Society of Periodontology
Mesotherapy using Vitamin C as an anti-inflammatory agent in persistent gingival inflammation: A case series.
Article in Journal of Indian Society of Periodontology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed, 9 citations in OpenAlex.
- Vitamin C mesotherapy versus diode laser for the esthetic management of physiologic gingival hyperpigmentation: a randomized clinical trial.BMC oral health · 2023Trial
- Evaluation of Serum Vitamin D and C Concentrations in Cats With Gingivostomatitis.Veterinary medicine and science · 2025Article
- Comparison of Various Minimally Invasive Techniques for the Management of Gingival Hyperpigmentation: A Case Report.Cureus · 2024Article
- A Minimally Invasive Technique for the Management of Physiologic Gingival Melanin Hyperpigmentation: A Case Series.Cureus · 2024Article
- The association between dietary vitamin C intake and periodontitis: result from the NHANES (2009-2014).BMC oral health · 2022Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMesotherapy is a minimally invasive procedure which involves local intradermal therapy (LIT) with biologically active substances given in minor quantities to the area of pathology. Vitamin C is an important antioxidant agent which can modulate the attenuation of inflammatory process and enhance tissue repair.
aimThe aim of this study was to investigate the efficacy of local injections of Vitamin C for treating persisting inflammation of the gingiva. MATERIALS AND
methodsAfter phase I therapy was completed, five patients with persisting chronic inflammation of the gingiva were injected with the same dosages of Vitamin C into the gingival tissues. Patients were evaluated each week for resolution of gingival inflammation.
resultsClinical observation showed a significant improvement in inflammation of the injected sites during recall appointments.
conclusionsLIT with Vitamin C has a synergistic interaction along with scaling and root planing in the treatment of persistent gingival inflammation.
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Registered trials
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