Evidence map›Paper›PMID 34158650›Full record

ArticleNature human behaviour2021

Despite vaccination, China needs non-pharmaceutical interventions to prevent widespread outbreaks of COVID-19 in 2021.

Juan Yang, Valentina Marziano, Xiaowei Deng, Giorgio Guzzetta, Juanjuan Zhang, Filippo Trentini, Jun Cai, Piero Poletti, Wen Zheng, Wei Wang and 8 more

Abstract read
In one paragraph

Article in Nature human behaviour, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
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  7. Changes in children respiratory infections pre and post COVID-19 pandemic.Frontiers in cellular and infection microbiology · 2025
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

18 authors.

Juan Yang *Shanghai Institute of Infectious Disease and Biosecurity, School of Public Health, Fudan University, Shanghai, China.ORCID http://orcid.org/0000-0001-5028-2227
Valentina Marziano *Center for Health Emergencies, Bruno Kessler Foundation, Trento, Italy.ORCID http://orcid.org/0000-0003-2842-7906
Xiaowei DengShanghai Institute of Infectious Disease and Biosecurity, School of Public Health, Fudan University, Shanghai, China.
Giorgio GuzzettaCenter for Health Emergencies, Bruno Kessler Foundation, Trento, Italy.ORCID http://orcid.org/0000-0002-9296-9470
Juanjuan ZhangShanghai Institute of Infectious Disease and Biosecurity, School of Public Health, Fudan University, Shanghai, China.
Filippo TrentiniCenter for Health Emergencies, Bruno Kessler Foundation, Trento, Italy.ORCID http://orcid.org/0000-0001-6915-7282
Jun CaiShanghai Institute of Infectious Disease and Biosecurity, School of Public Health, Fudan University, Shanghai, China.ORCID http://orcid.org/0000-0001-9495-1226
Piero PolettiCenter for Health Emergencies, Bruno Kessler Foundation, Trento, Italy.ORCID http://orcid.org/0000-0001-5453-5199
Wen ZhengShanghai Institute of Infectious Disease and Biosecurity, School of Public Health, Fudan University, Shanghai, China.
Wei WangShanghai Institute of Infectious Disease and Biosecurity, School of Public Health, Fudan University, Shanghai, China.
Qianhui WuShanghai Institute of Infectious Disease and Biosecurity, School of Public Health, Fudan University, Shanghai, China.
Zeyao ZhaoShanghai Institute of Infectious Disease and Biosecurity, School of Public Health, Fudan University, Shanghai, China.
Kaige DongShanghai Institute of Infectious Disease and Biosecurity, School of Public Health, Fudan University, Shanghai, China.
Guangjie ZhongShanghai Institute of Infectious Disease and Biosecurity, School of Public Health, Fudan University, Shanghai, China.
Cécile ViboudDivision of International Epidemiology and Population Studies, Fogarty International Center, National Institutes of Health, Bethesda, MD, USA.ORCID http://orcid.org/0000-0003-3243-4711
Stefano MerlerCenter for Health Emergencies, Bruno Kessler Foundation, Trento, Italy.
Marco AjelliDepartment of Epidemiology and Biostatistics, Indiana University School of Public Health, Bloomington, IN, USA. marco.ajelli@gmail.com.ORCID http://orcid.org/0000-0003-1753-4749
Hongjie YuShanghai Institute of Infectious Disease and Biosecurity, School of Public Health, Fudan University, Shanghai, China. yhj@fudan.edu.cn.ORCID http://orcid.org/0000-0002-6335-5648

Funding

China National Funds for Distinguished Young Scientists 81525023
6 · The paper itself

Abstract

COVID-19 vaccination is being conducted in over 200 countries and regions to control SARS-CoV-2 transmission and return to a pre-pandemic lifestyle. However, understanding when non-pharmaceutical interventions (NPIs) can be lifted as immunity builds up remains a key question for policy makers. To address this, we built a data-driven model of SARS-CoV-2 transmission for China. We estimated that, to prevent the escalation of local outbreaks to widespread epidemics, stringent NPIs need to remain in place at least one year after the start of vaccination. Should NPIs alone be capable of keeping the reproduction number (R

Indexed as

VaccinationChinaCOVID-19COVID-19 VaccinesDisease OutbreaksHumansCOVID-19 Vaccines

Identifiers

PMID34158650
PMCPMC8373613

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.