ArticleScientific reports2021
Neuroanatomical correlates of poststroke complex regional pain syndrome: a voxel-based lesion symptom-mapping study.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07428811 (Effects of Task-based Mirror Therapy on Edema, Pain and Upper Limb Motor Function for Post-stroke Shoulder-hand Syndrome), which is not on this map. Cited by 8 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of Task-based Mirror Therapy on Edema, Pain and Upper Limb Motor Function for Post-stroke Shoulder-hand Syndrome
Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A Meta-Analysis and Meta-Regression of Frequency and Risk Factors for Poststroke Complex Regional Pain Syndrome.Medicina (Kaunas, Lithuania) · 2021Pooled it
- Development and validation of a nomogram for early prediction of post-stroke shoulder-hand syndrome: a retrospective cohort study.Frontiers in neuroscience · 2026Article
- Current Clinical Applications of Structural MRI in Neurological Disorders.Journal of clinical neurology (Seoul, Korea) · 2025Review
- White matter tracts involved in complex regional pain syndrome after subcortical stroke.Frontiers in neurology · 2025Article
- A decision tree algorithm to identify predictors of post-stroke complex regional pain syndrome.Scientific reports · 2024Article
- A predictive model based on random forest for shoulder-hand syndrome.Frontiers in neuroscience · 2023Article
- Post-Stroke Complex Regional Pain Syndrome and Upper Limb Inactivity in Hemiplegic Patients: A Cross-Sectional Study.Journal of pain research · 2022Article
- The clinical effect of manual therapy including Tuina (or Chuna) on post-stroke shoulder hand syndrome-a literature review.Frontiers in neurologyReview
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Complex regional pain syndrome (CRPS) is a common poststroke complication. However, the neural substrates associated with CRPS remain unclear. We investigated the neural correlates associated with poststroke CRPS using voxel-based lesion‒symptom mapping (VLSM) analysis. Among 145 patients with ischemic stroke, 35 were diagnosed with CRPS and categorized into the poststroke CRPS group, and the remaining 110 into the control group. We compared the clinical characteristics between the groups. VLSM analysis was performed to identify the brain region associated with the development of poststroke CRPS. The clinical findings suggested that the poststroke CRPS group had lower muscle strength; lower scores on Fugl‒Meyer assessment, Manual Function Test, Mini-Mental Status Examination; and higher incidence of absent somatosensory evoked potentials in the median nerve than the control group. The head of the caudate nucleus, putamen, and white matter complexes in the corona radiata were significantly associated with poststroke CRPS development in ischemic stroke patients. These results facilitate an understanding of poststroke CRPS pathophysiology. Monitoring patients with lesions in these structures may aid the prevention and early treatment of poststroke CRPS.
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Registered trials
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