ArticleScientific reports2021
The impact of obesity on left ventricular hypertrophy and diastolic dysfunction in children and adolescents.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.
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Who cites it
26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 32 citations in OpenAlex.
- Obesity and Left Ventricular Mechanics in Children and Adolescents: A Systematic Review and Meta-Analysis.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2025Pooled it
- Cardiovascular implications in adolescent and young adult hypertension.Reviews in cardiovascular medicine · 2022Pooled it
- The relationship between blood pressure variability, left ventricular hypertrophy, and arterial stiffness in children and adolescents with obesity.Pediatric nephrology (Berlin, Germany) · 2026Article
- Ambulatory blood pressure characteristics and left ventricular hypertrophy in untreated children with primary hypertension.European journal of pediatrics · 2026Article
- Significance of the Echocardiographic Assessment of Longitudinal Left Ventricular Systolic Function in Children and Adolescents with Hypertrophic Cardiomyopathy.Journal of clinical medicine · 2026Article
- Gut Microbiome-Hormone Interactions and Precision Fermentation in the Prevention of Early Cardiovascular Risk in Adolescents.International journal of molecular sciences · 2026Review
- From Adiposity to Diastolic Dysfunction: The Integrated Role of Epicardial Fat, Autonomic Dysregulation, and Morning Blood Pressure Surge in Obesity.International journal of hypertension · 2026Article
- Prevalence of psychological and metabolic concerns in children with white coat and ambulatory hypertension.Frontiers in nephrology · 2026Article
- E/e' ratio combined with left ventricular mass index predicts HFpEF rehospitalization risk in stage 3-4 chronic kidney disease patients: a retrospective cohort study.Frontiers in cardiovascular medicine · 2026Article
- Obesity and Left Ventricular Function in American Indian Adolescents: Strong Heart Family Study.Journal of racial and ethnic health disparities · 2025Article
- Nocturnal hypertension predicts left ventricular hypertrophy in children with primary hypertension.Translational pediatrics · 2025Article
- The ratio of serum glucose to potassium is associated with poor prognosis in patients with severe acute myocardial infarction.Scientific reports · 2025Article
- Multimodality Imaging in Aldosterone-Induced Cardiomyopathy: Early Detection and Prognostic Implications.Diagnostics (Basel, Switzerland) · 2025Review
- The correlation between insulin-like growth factor 1 and left ventricular mass index in obese children.BMC endocrine disorders · 2025Article
- Echocardiographic nomograms in children living at high altitude according to sex.European heart journal. Imaging methods and practice · 2025Article
- Influence of hypertension and global or abdominal obesity on left ventricular hypertrophy: A cross-sectional study.Journal of clinical hypertension (Greenwich, Conn.) · 2024Article
- Relationship of Left Ventricular Mass to Lean Body Mass in the Obese Pediatric Population.Pediatric cardiology · 2024Article
- Impact of epicardial adipose tissue on diastolic dysfunction in patients with chronic coronary syndrome and preserved left ventricular ejection fraction.European heart journal. Imaging methods and practice · 2024Article
- Weight status change during four years and left ventricular hypertrophy in Chinese children.Frontiers in pediatrics · 2024Article
- Association between left ventricular remodeling and lipid profiles in obese children: an observational study.Frontiers in pediatrics · 2024Article
Corrections and comments
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Authors and funding
16 authors at 6 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Childhood obesity continues to escalate worldwide and may affect left ventricular (LV) geometry and function. The aim of this study was to investigate the impact of obesity on prevalence of left ventricular hypertrophy (LVH) and diastolic dysfunction in children. In this analysis of prospectively collected cross-sectional data of children between 5 and 16 years of age from randomly selected schools in Peru, parameters of LV geometry and function were compared according to presence or absence of obesity (body mass index z-score > 2). LVH was based on left ventricular mass index (LVMI) adjusted for age and sex and defined by a z-score of > 2. LV diastolic function was assessed using mitral inflow early-to-late diastolic flow (E/A) ratio, peak early diastolic tissue velocities of the lateral mitral annulus (E'), early diastolic transmitral flow velocity to tissue Doppler mitral annular early diastolic velocity (E/E') ratio, and left atrial volume index (LAVI). Among 1023 children, 681 children (mean age 12.2 ± 3.1 years, 341 male (50.1%)) were available for the present analysis, of which 150 (22.0%) were obese. LVH was found in 21 (14.0%) obese and in 19 (3.6%) non-obese children (p
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