ArticleScientific reports2021
Human brain dynamics in active spatial navigation.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07225400 (Designing a Spatial Navigation Intervention Protocol Informed by Region-specific Brain Activation for Mild Cognitive Impairment), which is not on this map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Designing a Spatial Navigation Intervention Protocol Informed by Region-specific Brain Activation for Mild Cognitive Impairment
Who cites it
20 citing papers in PubMed, 73 citations in OpenAlex.
- Neural synchrony and cognitive map formulation in collaborative navigation: leader-follower couplings revealed by EEG hyperscanning.Cognitive neurodynamics · 2026Article
- Neurocognitive Dynamics of Translating Information From a Spatial Map Into Action.Psychophysiology · 2026Article
- Cortical dynamics are differentially associated with decision-making strategies in human wayfinding: An EEG study.Cognitive, affective & behavioral neuroscience · 2026Article
- Bridging Space Perception, Emotions, and Artificial Intelligence in Neuroarchitecture.Brain sciences · 2026Review
- Theta oscillations are associated with movement during choreographed and improvised dance - a case series with Memphis Jookin': The Show.Research square · 2026Article
- A psychological network analysis of self-reported spatial cognitive strategies in commercial airline pilots and non-pilots.Frontiers in human neuroscience · 2026Article
- The effect of virtual reality modality level of immersion and locomotion on Spatial learning and gaze measures.Virtual reality · 2026Article
- Spatial navigation entropy suggests allocentric dysfunction in PPPD.Frontiers in neurology · 2025Article
- Imagine going left versus imagine going right: whole-body motion on the lateral axis.Scientific reports · 2024Article
- Multimodal fusion for anticipating human decision performance.Scientific reports · 2024Article
- An experimental framework for conjoint measures of olfaction, navigation, and motion as pre-clinical biomarkers of Alzheimer's disease.Journal of Alzheimer's disease reports · 2024Review
- Spatial memory and learning: investigating the role of dynamic visual acuity.Frontiers in behavioral neuroscience · 2024Article
- Understanding the effects of stress on the P300 response during naturalistic simulation of heights exposure.PloS one · 2024Article
- Investigating the different domains of environmental knowledge acquired from virtual navigation and their relationship to cognitive factors and wayfinding inclinations.Cognitive research: principles and implications · 2023Article
- Bidirectional understanding and cooperation: interbrain neural synchronization during social navigation.Social cognitive and affective neuroscience · 2023Article
- Mobile cognition: imaging the human brain in the 'real world'.Nature reviews. Neuroscience · 2023Review
- Review
- Using spontaneous eye blink-related brain activity to investigate cognitive load during mobile map-assisted navigation.Frontiers in neuroscience · 2023Article
- The Promises and Pitfalls of Virtual Reality.Current topics in behavioral neurosciences · 2023Article
- EEG analysis of the visual motion activated vection network in left- and right-handers.Scientific reports · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Spatial navigation is a complex cognitive process based on multiple senses that are integrated and processed by a wide network of brain areas. Previous studies have revealed the retrosplenial complex (RSC) to be modulated in a task-related manner during navigation. However, these studies restricted participants' movement to stationary setups, which might have impacted heading computations due to the absence of vestibular and proprioceptive inputs. Here, we present evidence of human RSC theta oscillation (4-8 Hz) in an active spatial navigation task where participants actively ambulated from one location to several other points while the position of a landmark and the starting location were updated. The results revealed theta power in the RSC to be pronounced during heading changes but not during translational movements, indicating that physical rotations induce human RSC theta activity. This finding provides a potential evidence of head-direction computation in RSC in healthy humans during active spatial navigation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.