Evidence map›Paper›PMID 34158489›Full record

ArticleNature communications2021

Acoustoelectronic nanotweezers enable dynamic and large-scale control of nanomaterials.

Peiran Zhang, Joseph Rufo, Chuyi Chen, Jianping Xia, Zhenhua Tian, Liying Zhang, Nanjing Hao, Zhanwei Zhong, Yuyang Gu, Krishnendu Chakrabarty and 1 more

Abstract read
In one paragraph

Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Article
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  13. Swarm Autonomy: From Agent Functionalization to Machine Intelligence.Advanced materials (Deerfield Beach, Fla.) · 2025
    Review
  14. Review
  15. Article
  16. Article
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  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Peiran Zhang *Department of Mechanical Engineering and Materials Science, Duke University, Durham, NC, USA.
Joseph Rufo *Department of Mechanical Engineering and Materials Science, Duke University, Durham, NC, USA.
Chuyi ChenDepartment of Mechanical Engineering and Materials Science, Duke University, Durham, NC, USA.ORCID 0000-0001-5733-4261
Jianping XiaDepartment of Mechanical Engineering and Materials Science, Duke University, Durham, NC, USA.ORCID 0000-0001-9902-0228
Zhenhua TianDepartment of Mechanical Engineering and Materials Science, Duke University, Durham, NC, USA.
Liying ZhangDepartment of Mechanical Engineering and Materials Science, Duke University, Durham, NC, USA.
Nanjing HaoDepartment of Mechanical Engineering and Materials Science, Duke University, Durham, NC, USA.ORCID 0000-0003-3808-7941
Zhanwei ZhongDepartment of Electrical and Computer Engineering, Duke University, Durham, NC, USA.
Yuyang GuDepartment of Mechanical Engineering and Materials Science, Duke University, Durham, NC, USA.
Krishnendu ChakrabartyDepartment of Electrical and Computer Engineering, Duke University, Durham, NC, USA.
Tony Jun HuangDepartment of Mechanical Engineering and Materials Science, Duke University, Durham, NC, USA. tony.huang@duke.edu.ORCID 0000-0003-1205-3313

Funding

AFS/SERS Saliva-based SARS-CoV-2 Earliest Infection and Antibodies DetectionU18TR003778 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI HUANG, TONY JUN, KIM, YONG · 2021 to 2022
$1.8M
Integrated Acoustofluidic Plasmonic Molecular Diagnostic System for Detecting MicroRNA BiomarkersR01GM135486 · NIGMS · DUKE UNIVERSITY · PI VO-DINH, TUAN · 2020 to 2023
$1.8M
Enabling Efficient, Fast, Biocompatible Exosome Separation via AcoustofluidicsR01GM132603 · NIGMS · DUKE UNIVERSITY · PI HUANG, TONY JUN · 2019 to 2022
$1.7M
Determining treatment sensitivity in B cell lymphoma by novel microfluidics-based NK cell immunogenicity platformR33CA223908 · NCI · NORTHEASTERN UNIVERSITY · PI EVENS, ANDREW M, HUANG, TONY JUN · 2018 to 2020
$1.2M
An integrated acoustofluidic droplet-sorting platform for classification of lymphocyte activity and functional phenotyping at single cell levelR01GM127714 · NIGMS · NORTHEASTERN UNIVERSITY · PI KONRY, TANIA TALI · 2018 to 2021
$1.2M
Acoustofluidic Separation (AFS), Purification and Raman Spectral Fingerprinting of Single EVs: From Cell of Origin to Target Cell and BiofluidsUG3TR002978 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI AN, JI YEONG, GALL, KENNETH A · 2019 to 2020
$823k
NCATS NIH HHS U18 TR003778NCATS NIH HHS UG3 TR002978NCI NIH HHS R33 CA223908NIGMS NIH HHS R01 GM127714NIGMS NIH HHS R01 GM132603NIGMS NIH HHS R01 GM135486
6 · The paper itself

Abstract

The ability to precisely manipulate nano-objects on a large scale can enable the fabrication of materials and devices with tunable optical, electromagnetic, and mechanical properties. However, the dynamic, parallel manipulation of nanoscale colloids and materials remains a significant challenge. Here, we demonstrate acoustoelectronic nanotweezers, which combine the precision and robustness afforded by electronic tweezers with versatility and large-field dynamic control granted by acoustic tweezing techniques, to enable the massively parallel manipulation of sub-100 nm objects with excellent versatility and controllability. Using this approach, we demonstrated the complex patterning of various nanoparticles (e.g., DNAs, exosomes, ~3 nm graphene flakes, ~6 nm quantum dots, ~3.5 nm proteins, and ~1.4 nm dextran), fabricated macroscopic materials with nano-textures, and performed high-resolution, single nanoparticle manipulation. Various nanomanipulation functions, including transportation, concentration, orientation, pattern-overlaying, and sorting, have also been achieved using a simple device configuration. Altogether, acoustoelectronic nanotweezers overcome existing limitations in nano-manipulation and hold great potential for a variety of applications in the fields of electronics, optics, condensed matter physics, metamaterials, and biomedicine.

Indexed as

Optical TweezersAcousticsColloidsDNAElectronicsExosomesMetal NanoparticlesNanostructuresNanotechnologyNanotubes, CarbonParticle SizeReproducibility of ResultsColloidsDNANanotubes, Carbon

Identifiers

PMID34158489
PMCPMC8219664

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.