ArticleNature communications2021
Toxoplasma gondii infections are associated with costly boldness toward felids in a wild host.
Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed.
- Delayed Pathogenicity inMicroorganisms · 2026Article
- Fallow deer approaching humans are more likely to be seropositive forRoyal Society open science · 2025Article
- Molecular detection and characterisation ofInternational journal for parasitology. Parasites and wildlife · 2025Article
- Ectoparasites enhance survival by suppressing host exploration and limiting dispersal.Nature communications · 2025Article
- Thirty years of studying latent toxoplasmosis: behavioural, physiological, and health insights.Folia parasitologica · 2025Review
- Seroprevalence ofPathogens (Basel, Switzerland) · 2025Article
- Social context influences Toxoplasma gondii and Trichinella spp. infection in Alberta free-roaming wild pigs (Sus scrofa).PloS one · 2025Article
- Exploring similarities and differences between Toxoplasma gondii and Neospora caninum infections in dogs.Veterinary research communications · 2024Review
- Legal provisions on medical aid in dying encode moral intuition.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Development of an indirect ELISA for detecting Toxoplasma gondii IgG antibodies based on a recombinant TgIMP1 protein.PLoS neglected tropical diseases · 2024Article
- The effect of parasitism on boldness and sheltering behaviour in albino and pigmented European catfish (Silurus glanis).Scientific reports · 2024Article
- Intestinal microbiota imbalance resulted by anti-Toxoplasma gondii immune responses aggravate gut and brain injury.Parasites & vectors · 2024Article
- The role of species ecology in predicting Toxoplasma gondii prevalence in wild and domesticated mammals globally.PLoS pathogens · 2024Article
- Parasite-mediated manipulation?Biology letters · 2023Article
- Molecular Survey ofPathogens (Basel, Switzerland) · 2023Article
- Article
- Parasitic infection increases risk-taking in a social, intermediate host carnivore.Communications biology · 2022Article
- Applications of conceptual models from lifecourse epidemiology in ecology and evolutionary biology.Biology letters · 2022Review
- Examination of the interaction between age-specific predation and chronic disease in the Greater Yellowstone Ecosystem.The Journal of animal ecology · 2022Article
- Associations betweenInternational journal for parasitology. Parasites and wildlife · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
Abstract
Toxoplasma gondii is hypothesized to manipulate the behavior of warm-blooded hosts to promote trophic transmission into the parasite's definitive feline hosts. A key prediction of this hypothesis is that T. gondii infections of non-feline hosts are associated with costly behavior toward T. gondii's definitive hosts; however, this effect has not been documented in any of the parasite's diverse wild hosts during naturally occurring interactions with felines. Here, three decades of field observations reveal that T. gondii-infected hyena cubs approach lions more closely than uninfected peers and have higher rates of lion mortality. We discuss these results in light of 1) the possibility that hyena boldness represents an extended phenotype of the parasite, and 2) alternative scenarios in which T. gondii has not undergone selection to manipulate behavior in host hyenas. Both cases remain plausible and have important ramifications for T. gondii's impacts on host behavior and fitness in the wild.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.