Evidence map›Paper›PMID 34158483›Full record

ReviewNature communications2021

Nanophotonic biosensors harnessing van der Waals materials.

Sang-Hyun Oh, Hatice Altug, Xiaojia Jin, Tony Low, Steven J Koester, Aleksandar P Ivanov, Joshua B Edel, Phaedon Avouris, Michael S Strano

Open access · goldAbstract readReview
In one paragraph

Review in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed
9.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 146 citations in OpenAlex.

  1. Review
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  6. Review
  7. Article
  8. Review
  9. Article
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  11. Atomistic QM/Classical Modeling of Surface-Enhanced Infrared Absorption.The journal of physical chemistry. C, Nanomaterials and interfaces · 2026
    Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Advances in 2D materials for wearable biomonitoring.Materials science & engineering. R, Reports : a review journal · 2025
    Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

Sang-Hyun OhDepartment of Electrical and Computer Engineering, University of Minnesota, Minneapolis, MN, USA. sang@umn.edu.ORCID 0000-0002-6992-5007
Hatice AltugInstitute of Bioengineering, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland. hatice.altug@epfl.ch.ORCID 0000-0001-5522-1343
Xiaojia JinDepartment of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.ORCID 0000-0002-0694-5799
Tony LowDepartment of Electrical and Computer Engineering, University of Minnesota, Minneapolis, MN, USA.
Steven J KoesterDepartment of Electrical and Computer Engineering, University of Minnesota, Minneapolis, MN, USA.
Aleksandar P IvanovDepartment of Chemistry, Imperial College London, London, UK.ORCID 0000-0003-1419-1381
Joshua B EdelDepartment of Chemistry, Imperial College London, London, UK.ORCID 0000-0001-5870-8659
Phaedon AvourisIBM T. J. Watson Research Center, New York, NY, USA.
Michael S StranoDepartment of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA. strano@mit.edu.ORCID 0000-0003-2944-808X
University of Minnesota · USImperial College London · GBÉcole Polytechnique Fédérale de Lausanne · CHIIT@MIT · USMassachusetts Institute of Technology · US

Funding

Biotechnology and Biological Sciences Research Council BB/R022429/1
6 · The paper itself

Abstract

Low-dimensional van der Waals (vdW) materials can harness tightly confined polaritonic waves to deliver unique advantages for nanophotonic biosensing. The reduced dimensionality of vdW materials, as in the case of two-dimensional graphene, can greatly enhance plasmonic field confinement, boosting sensitivity and efficiency compared to conventional nanophotonic devices that rely on surface plasmon resonance in metallic films. Furthermore, the reduction of dielectric screening in vdW materials enables electrostatic tunability of different polariton modes, including plasmons, excitons, and phonons. One-dimensional vdW materials, particularly single-walled carbon nanotubes, possess unique form factors with confined excitons to enable single-molecule detection as well as in vivo biosensing. We discuss basic sensing principles based on vdW materials, followed by technological challenges such as surface chemistry, integration, and toxicity. Finally, we highlight progress in harnessing vdW materials to demonstrate new sensing functionalities that are difficult to perform with conventional metal/dielectric sensors.

Indexed as

Biocompatible MaterialsBiosensing TechniquesGraphiteMetalsNanostructuresParticle SizeSpectrophotometry, InfraredSurface Plasmon ResonanceSurface PropertiesThermodynamicsBiocompatible MaterialsGraphiteMetals

Identifiers

PMID34158483
PMCPMC8219843
OpenAlexW3173889280

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.