Evidence map›Paper›PMID 34158329›Full record

ArticleBMJ case reports2021

Osteolytic lesions as the sole presenting feature of secondary syphilis.

Matthew Colquhoun, Othman Kirresh, Mohammad Keikha, Lewis Haddow

Abstract readCase Reports
In one paragraph

Article in BMJ case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Matthew ColquhounRheumatology, Northwick Park Hospital, Harrow, UK matthew.colquhoun@nhs.net.ORCID http://orcid.org/0000-0001-6736-5678
Othman KirreshRheumatology, West Middlesex University Hospital, Isleworth, London, UK.
Mohammad KeikhaRadiology, West Middlesex Hospital, London, UK.
Lewis HaddowHIV and Genitourinary Medicine, Kingston Hospital NHS Foundation Trust, Kingston upon Thames, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present the case of a 48-year-old man with a background of well-controlled HIV who presented with bony pain in multiple regions and raised inflammatory markers. After an investigative process, the patient was newly diagnosed with secondary syphilis. Bony pain, secondary to osteolytic lesions and demonstrated on plain radiography, CT and nuclear medicine imaging, was the sole presenting feature. The patient was successfully treated with penicillin G and his symptoms improved. Rheumatologists are often tasked with diagnosing the cause of a patient's pain. However, in this case, a multidisciplinary approach was needed and the contribution of a specialist in Genitourinary Medicine/HIV was required to help diagnose this rare cause of bony pain.

Indexed as

OsteolysisSyphilisHumansMaleMiddle AgedPenicillin GRadiographyPenicillin Gbone and joint infectionsmusculoskeletal syndromespublic health

Identifiers

PMID34158329
PMCPMC8220520

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.