ArticleLaboratory animal research2021
A comparative study on intraocular pressure under various anesthetics in cynomolgus monkeys (Macaca fascicularis).
Article in Laboratory animal research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
3 citing papers in PubMed, 4 citations in OpenAlex.
- Ex Vivo Validation of the TONOVET Plus and TONOVET Pro in Cynomolgus Monkeys (Macaca fascicularis): Comparison of Canine and Lapine Calibration Modes.Veterinary ophthalmology · 2026Article
- Diurnal Variation and Effects of Dilation and Sedation on Intraocular Pressure in Infant Rhesus Monkeys.Current eye research · 2023Article
- Xylazine in the Opioid Epidemic: A Systematic Review of Case Reports and Clinical Implications.Cureus · 2023Review
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
backgroundNonhuman primates (NHPs) are superior model for ocular research due to its morphological and physiological similarities with humans. Thus, the effect of four different anesthetic combinations [ketamine (10 mg/kg), ketamine + xylazine (7 + 0.6 mg/kg), zoletil (4 mg/kg), and zoletil + xylazine (4 + 0.2 mg/kg)] on intraocular pressure (IOP) was determined in cynomolgus monkeys.
resultsThe administration of ketamine + xylazine or zoletil + xylazine resulted in lower IOP compared to ketamine or zoletil alone. Moreover, the IOP in male monkeys was higher than in females. The difference between the right and left eye was not found.
conclusionsAnesthetics affected the IOP, and gender differences should be considered when measuring the IOP of nonhuman primates (NHPs).
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Registered trials
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