Evidence map›Paper›PMID 34158018›Full record

ArticleBMC musculoskeletal disorders2021

Whether sutures reduce the graft laceration caused by interference screw in anterior cruciate ligament reconstruction? A biomechanical study in vitro.

Yuanjun Teng, Xiaohui Zhang, Lijun Da, Jie Hu, Hong Wang, Hua Han, Meng Wu, Shifeng Zhang, Yayi Xia

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in BMC musculoskeletal disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07023653 (Comparison of Clinical Outcomes Between All-Inside and Complete Tibial Tunnel Techniques in Anterior Cruciate Ligament Reconstruction Among Patients With ACL Ruptures), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07023653 narecruitingnot on this mapstarted 2024, after this paper: background citation

Comparison of Clinical Outcomes Between All-Inside and Complete Tibial Tunnel Techniques in Anterior Cruciate Ligament Reconstruction Among Patients With ACL Ruptures

TypeinterventionalSponsorIndonesia UniversityRan2024 to 2026Enrolled40ConditionsAnterior Cruciate Ligament RuptureArmsAll-Inside Techniques, Complete Tibial Tunnel techniques
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Yuanjun TengDepartment of Orthopaedics, Lanzhou University Second Hospital, Lanzhou University, No. 82 Cuiyingmen, Chengguan District, 730030, Lanzhou City, Gansu Province, People's Republic of China.
Xiaohui ZhangDepartment of Orthopaedics, Lanzhou University Second Hospital, Lanzhou University, No. 82 Cuiyingmen, Chengguan District, 730030, Lanzhou City, Gansu Province, People's Republic of China.
Lijun DaDepartment of Oncology, Lanzhou University Second Hospital, Lanzhou University, 730030, Lanzhou City, Gansu Province, People's Republic of China.
Jie HuThe Second Clinical Medical College, Lanzhou University, 730030, Lanzhou City, Gansu Province, People's Republic of China.
Hong WangDepartment of Orthopaedics, Lanzhou University Second Hospital, Lanzhou University, No. 82 Cuiyingmen, Chengguan District, 730030, Lanzhou City, Gansu Province, People's Republic of China.
Hua HanDepartment of Orthopaedics, Lanzhou University Second Hospital, Lanzhou University, No. 82 Cuiyingmen, Chengguan District, 730030, Lanzhou City, Gansu Province, People's Republic of China.
Meng WuDepartment of Orthopaedics, Lanzhou University Second Hospital, Lanzhou University, No. 82 Cuiyingmen, Chengguan District, 730030, Lanzhou City, Gansu Province, People's Republic of China.
Shifeng ZhangDepartment of Orthopaedics, Lanzhou University Second Hospital, Lanzhou University, No. 82 Cuiyingmen, Chengguan District, 730030, Lanzhou City, Gansu Province, People's Republic of China.
Yayi XiaDepartment of Orthopaedics, Lanzhou University Second Hospital, Lanzhou University, No. 82 Cuiyingmen, Chengguan District, 730030, Lanzhou City, Gansu Province, People's Republic of China. xiayayilzu@126.com.
Lanzhou University · CNLanzhou University Second Hospital · CN

Funding

Cuiying Science and Technology Innovation Project of Lanzhou University Second Hospital CY2019-QN02Innovation Fund for Universities in Gansu Province 2020B-029National Natural Science Foundation of China 82060413/81874017/81960403/82060405Project of TCM Inheritance and Innovation Platform Construction TCM-IPC-2020-04Science and Technology Project of Chengguan District/Lanzhou City 2020JSCX0071/2020-2-2-10
6 · The paper itself

Abstract

backgroundInterference screw is commonly used for graft fixation in anterior cruciate ligament (ACL) reconstruction. However, previous studies had reported that the insertion of interference screws significantly caused graft laceration. The purposes of this study were to (1) quantitatively evaluate the graft laceration from one single insertion of PEEK interference screws; and (2) determine whether different types of sutures reduced the graft laceration after one single insertion of interference screws in ACL reconstruction.

methodsThe in-vitro ACL reconstruction model was created using porcine tibias and bovine extensor digitorum tendons of bovine hind limbs. The ends of grafts were sutured using three different sutures, including the bioabsorbable, Ethibond and ultra-high molecular weight polyethylene (UHMWPE) sutures. Poly-ether-ether-ketone (PEEK) interference screws were used for tibial fixation. This study was divided into five groups (n = 10 in each group): the non-fixed group, the non-sutured group, the absorbable suture group, the Ethibond suture group and the UHMWPE suture group. Biomechanical tests were performed using the mode of pull-to-failure loading tests at 10 mm/min. Tensile stiffness (newtons per millimeter), energy absorbed to failure (in joules) and ultimate load (newtons) were recorded for analysis.

resultsAll prepared tendons and bone specimens showed similar characteristics (length, weight, and pre-tension of the tendons, tibial bone mineral density) among all groups (P > 0.05). The biomechanical tests demonstrated that PEEK interference screws significantly caused the graft laceration (P < 0.05). However, all sutures (the bioabsorbable, Ethibond and UHMWPE sutures) did not reduce the graft laceration in ACL reconstruction (P > 0.05).

conclusionsOur biomechanical study suggested that the ultimate failure load of grafts was reduced of approximately 25 % after one single insertion of a PEEK interference screw in ACL reconstruction. Suturing the ends of the grafts using different sutures (absorbable, Ethibond and UHMWPE sutures) did not decrease the graft laceration caused by interference screws.

Indexed as

Anterior Cruciate Ligament ReconstructionLacerationsAnimalsAnterior Cruciate LigamentBiomechanical PhenomenaBone ScrewsCattleSuturesSwineTibiaAnterior cruciate ligament reconstructionBiomechanical studyGraft lacerationInterference screwsSuture

Identifiers

PMID34158018
PMCPMC8218482
OpenAlexW3126002032

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.