ArticleBMC infectious diseases2021
Measles outbreak in Western Uganda: a case-control study.
Article in BMC infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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10 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.
- The quality of measles outbreak investigation report, how can it bridge the gap and help to fulfill the goal of measles elimination?BMC infectious diseases · 2025Pooled it
- School-associated measles outbreak driven by vaccination gaps, sociocultural barriers, and delayed detection in Gomba District, Uganda 2025.Discover public health · 2026Article
- [Measles during migration: lessons learned in Colombia, 2018-2019O sarampo durante a migração: lições aprendidas na Colômbia, 2018-2019].Revista panamericana de salud publica = Pan American journal of public health · 2025Article
- Trends of measles in Tanzania: A 5-year review of case-based surveillance data, 2018-2022.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2024Article
- Public health and research ethics education: the experience of developing a new cadre of bioethicists at a Ugandan institution.BMC medical education · 2024Article
- Measles Outbreaks in the Republic of Congo: Epidemiology of Laboratory-Confirmed Cases Between 2019 and 2022.Advances in virology · 2024Article
- Measles outbreak in sub-Saharan Africa amidst COVID-19: A rising concern, efforts, challenges, and future recommendations.Annals of medicine and surgery (2012) · 2022Article
- Gaps in measles vaccination coverage in Kasese district, Western Uganda: results of a qualitative evaluation.BMC infectious diseases · 2022Article
- Exploring infant feeding practices and associated factors among HIV-positive mothers attending early infant diagnosis clinic in Northern Uganda.Epidemiology and infection · 2022Article
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Authors and funding
12 authors at 3 institutions in 3 countries.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundMeasles outbreaks are prevalent throughout sub-Saharan Africa despite the preventive measures like vaccination that target under five-year-old children and health systems strengthening efforts like prioritizing the supply chain for supplies. Measles immunization coverage for Kasese district and Bugoye HC III in 2018 was 72 and 69%, respectively. This coverage has been very low and always marked red in the Red categorization (below the national target/poor performing) on the national league table indicators. The aim of this study was to assess the scope of the 2018-2019 measles outbreak and the associated risk factors among children aged 0-60 months in Bugoye sub-county, Kasese district, western Uganda.
methodsWe conducted a retrospective unmatched case-control study among children aged 0-60 months with measles (cases) who had either a clinical presentation or a laboratory confirmation (IgM positivity) presenting at Bugoye Health Centre III (BHC) or in the surrounding communities between December 2018 and October 2019.. Caregivers of the controls (whose children did not have measles) were selected at the time of data collection in July 2020. A modified CDC case investigation form was used in data collection. Quantitative data was collected and analyzed using Microsoft excel and STATA version 13. The children's immunization cards and health registers at BHC were reviewed to ascertain the immunization status of the children before the outbreak.
resultsAn extended measles outbreak occurred in Bugoye, Uganda occured between December 2018 and October 2019. All 34 facility-based measles cases were documented to have had maculopapular rash, conjunctivitis, and cough. Also, the majority had fever (97%), coryza (94.1%), lymphadenopathy (76.5%), arthralgias (73.5%) and Koplik Spots (91.2%) as documented in the clinical registers. Similar symptoms were reported among 36 community-based cases. Getting infected even after immunized, low measles vaccination coverage were identified as the principal risk factors for this outbreak.
conclusionMeasles is still a significant problem. This study showed that this outbreak was associated with under-vaccination. Implementing a second routine dose of measles-rubella vaccine would not only increase the number of children with at least one dose but also boost the immunity of those who had the first dose.
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