Observational studyRenal failure2021
Acute kidney injury in idiopathic membranous nephropathy with nephrotic syndrome.
Observational study in Renal failure, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06071533 (Effectiveness and Safety of Danshen Injection for Acute Kidney Injury in Primary Nephrotic Syndrome), which is not on this map. Cited by 10 papers.
What it found
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The trial behind it
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Effectiveness and Safety of Danshen Injection for Acute Kidney Injury in Primary Nephrotic Syndrome
Who cites it
10 citing papers in PubMed, 11 citations in OpenAlex.
- [Risk Factors for Idiopathic Membranous Nephropathy Complicated by Acute Kidney Injury].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2026Article
- Title-effectiveness and safety of Danshen injection for acute kidney injury in primary nephrotic syndrome.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2026Article
- Prognostic Factors of Proteinuria Remission in Primary Membranous Nephropathy.Journal of clinical medicine · 2025Review
- Article
- Fractional excretion of total protein predicts renal prognosis in Japanese patients with primary membranous nephropathy.Clinical kidney journal · 2024Article
- Acute kidney injury in patients with idiopathic membranous nephropathy: influencing factors and prognosis.Renal failure · 2023Article
- Non-diabetic urine glucose in idiopathic membranous nephropathy.Renal failure · 2022Article
- Prediction model of renal function recovery for primary membranous nephropathy with acute kidney injury.BMC nephrology · 2022Article
- Acute kidney injury in patients with primary nephrotic syndrome: influencing factors and coping strategies.BMC nephrology · 2022Article
- NELL-1 Associated Membranous Nephropathy - A Case Series from India.Indian journal of nephrologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
objectivesThe impact of acute kidney injury (AKI) on the progression of renal function in idiopathic membranous nephropathy (iMN) with nephrotic syndrome (NS) patients have not yet been reported, we sought to investigate the incidence, clinical features and prognosis of AKI in iMN with NS patients and determine clinical predictors for progression from AKI to advanced chronic kidney disease (CKD) stage.
methodsWe analyzed clinical and pathological data of iMN with NS patients retrospectively collected from Jan 2012 to Dec 2018. The primary renal endpoint was defined as persistent eGFR <45ml/min per 1.73 m
results434 iMN with NS patients were enrolled. The incidence of AKI 1 stage, AKI 2 stage and AKI 3 stage was 23.1, 4.8 and 0.7% respectively. 66 (53.2%) patients with AKI had complete renal function recovery and 42 (33.9%) patients with AKI reached primary renal endpoint. Survival without primary renal endpoint was worse in AKI patients than No AKI patients (67.1 ± 5.3 and 43.7 ± 7.3% vs 99.5 ± 0.5 and 92.5 ± 4.2% at 2 and 4 years,
conclusionsAKI was usually mild and overlooked in iMN patients with NS, but it had a strong association with poor clinical outcomes and was an independent risk factor for CKD progression.
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