Evidence map›Paper›PMID 34157707›Full record

ArticlePhysics in medicine and biology2021

Deconvolution-based partial volume correction of PET images with parallel level set regularization.

Yansong Zhu, Murat Bilgel, Yuanyuan Gao, Olivier G Rousset, Susan M Resnick, Dean F Wong, Arman Rahmim

Abstract read
In one paragraph

Article in Physics in medicine and biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. On the partial volume effect in magnetic particle imaging.Physics in medicine and biology · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yansong ZhuDepartment of Electrical and Computer Engineering, Johns Hopkins University, Baltimore, MD, United States of America.ORCID 0000-0002-3877-9369
Murat BilgelLaboratory of Behavioral Neuroscience, National Institute on Aging, Baltimore, MD, United States of America.
Yuanyuan GaoSchool of Biomedical Engineering, Southern Medical University, Guangzhou, People's Republic of China.
Olivier G RoussetDepartment of Radiology and Radiological Science, Johns Hopkins University, Baltimore, MD, United States of America.
Susan M ResnickLaboratory of Behavioral Neuroscience, National Institute on Aging, Baltimore, MD, United States of America.
Dean F WongMallinckrodt Institute of Radiology, Washington University in St. Louis, St. Louis, MO, United States of America.
Arman RahmimDepartment of Radiology and Radiological Science, Johns Hopkins University, Baltimore, MD, United States of America.ORCID 0000-0002-9980-2403

Funding

Neuroimaging Predictors of Cognitive Decline, Impairment, and ResilienceZIAAG000191 · NIA · NATIONAL INSTITUTE ON AGING · PI FERRUCCI, LUIGI · 2009 to 2025
$26.4M
Partial Volume Correction Methods to Improve Quantitation and Interpretation of Amyloid & Tau PET Imaging in Aging and DementiaR21AG056142 · NIA · JOHNS HOPKINS UNIVERSITY · PI RAHMIM, ARMAN, ROUSSET, OLIVIER · 2017 to 2018
$450k
Intramural NIH HHS Z99 AG999999NIA NIH HHS R21 AG056142
6 · The paper itself

Abstract

The partial volume effect (PVE), caused by the limited spatial resolution of positron emission tomography (PET), degrades images both qualitatively and quantitatively. Anatomical information provided by magnetic resonance (MR) images has the potential to play an important role in partial volume correction (PVC) methods. Post-reconstruction MR-guided PVC methods typically use segmented MR tissue maps, and further, assume that PET activity distribution is uniform in each region, imposing considerable constraints through anatomical guidance. In this work, we present a post-reconstruction PVC method based on deconvolution with parallel level set (PLS) regularization. We frame the problem as an iterative deconvolution task with PLS regularization that incorporates anatomical information without requiring MR segmentation or assuming uniformity of PET distributions within regions. An efficient algorithm for non-smooth optimization of the objective function (invoking split Bregman framework) is developed so that the proposed method can be feasibly applied to 3D images and produces sharper images compared to PLS method with smooth optimization. The proposed method was evaluated together with several other PVC methods using both realistic simulation experiments based on the BrainWeb phantom as well as

Indexed as

BrainImage Processing, Computer-AssistedAlgorithmsMagnetic Resonance ImagingPhantoms, ImagingPositron-Emission Tomographyanatomical priordeconvolutionpartial volume correction (PVC)positron emission tomography (PET)

Identifiers

PMID34157707
PMCPMC9614703

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.