Evidence map›Paper›PMID 34157423›Full record

ReviewPharmacological research2021

Ultra low doses and biological amplification: Approaching Avogadro's number.

Edward J Calabrese, James Giordano

Abstract readReview
In one paragraph

Review in Pharmacological research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Signalling of Adrenoceptors: Canonical Pathways and New Paradigms.Handbook of experimental pharmacology · 2024
    Review
  5. Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Edward J CalabreseProfessor of Toxicology, Environmental Health Sciences, Morrill I, N344, University of Massachusetts, Amherst, MA 01003, USA. Electronic address: edwardc@schoolph.umass.edu.
James GiordanoProfessor of Neurology and Biochemistry, Georgetown University Medical Center, Washington, DC 20057, USA. Electronic address: james.giordano@georgetown.edu.

Funding

Maternal Morbidity and Mortality: Risk Factors, Early Detection and Personalized InterventionUL1TR001409 · NCATS · GEORGETOWN UNIVERSITY · PI GONDRE-LEWIS, MARJORIE C, MELLMAN, THOMAS A · 2015 to 2024
$37.8M
NCATS NIH HHS UL1 TR001409
6 · The paper itself

Abstract

This paper describes evidence establishing that ultra-low doses of diverse chemical agents at concentrations from 10

Indexed as

Models, BiologicalAnimalsDose-Response Relationship, DrugFullerenesHormesisHumansLigandsOligopeptidesPhagocytosisPheromonesReceptors, G-Protein-CoupledSignal TransductionTetrahymenaFullerenesLigandsOligopeptidesPheromonesReceptors, G-Protein-CoupledAvogadro’s constantBiological amplificationHormesisPheromoneUltra-low dose

Identifiers

PMID34157423
PMCPMC8338887

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.