Evidence map›Paper›PMID 34157090›Full record

ArticleThe British journal of surgery2021

Global attitudes in the management of acute appendicitis during COVID-19 pandemic: ACIE Appy Study.

B Ielpo, M Podda, G Pellino, F Pata, R Caruso, G Gravante, S Di Saverio, ACIE Appy Study Collaborative

Registry-linked trialAbstract read
In one paragraph

Article in The British journal of surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05323851 (How Future Surgery Will Benefit From Severe Acute Respiratory Syndrome Coronavirus 2), which is not on this map. Cited by 37 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05323851 completednot on this mapstarted 2022, after this paper: background citation

How Future Surgery Will Benefit From Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Related Measures Perspective From Italian Young Surgeon Society (SPIGC)

TypeobservationalSponsorUniversity of Rome Tor VergataRan2022 to 2022Enrolled581ConditionsCOVID-19, Health BehaviorArmsCOVID-surg-SPIGC questionnaire
3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Appendectomy versus antibiotic treatment for acute appendicitis.The Cochrane database of systematic reviews · 2024
    Pooled it
  2. Trial
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  5. Acute appendicitis and its treatment: a historical overview.International journal of colorectal disease · 2025
    Article
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  15. What has changed in children's appendicitis during the COVID-19 pandemic?Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2022
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  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

B IelpoDepartment of Surgery, Hepatopancreatobiliary Unit, University Hospital Leon, Leon, Spain.ORCID 0000-0003-3129-3208
M PoddaDepartment of General and Emergency Surgery, Cagliari University Hospital, Azienda Ospedaliero-Universitaria, Cagliari, Italy.ORCID 0000-0001-9941-0883
G PellinoColorectal Surgery, Vall d'Hebron University Hospital, Barcelona, Spain.ORCID 0000-0002-8322-6421
F PataGeneral Surgery Unit, Nicola Giannettasio Hospital, Corigliano-Rossano, Italy.ORCID 0000-0003-2634-1199
R CarusoHospital Universitario HM Sanchinarro, Madrid, Spain.
G GravanteDepartment of General Surgery, Ospedale 'Francesco Ferrari', Casarano, Italy.
S Di SaverioDepartment of General Surgery, University of Insubria, University Hospital of Varese, ASST Sette Laghi, Regione LombardiaVarese, Italy.ORCID 0000-0001-5685-5022
ACIE Appy Study Collaborative

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSurgical strategies are being adapted to face the COVID-19 pandemic. Recommendations on the management of acute appendicitis have been based on expert opinion, but very little evidence is available. This study addressed that dearth with a snapshot of worldwide approaches to appendicitis.

methodsThe Association of Italian Surgeons in Europe designed an online survey to assess the current attitude of surgeons globally regarding the management of patients with acute appendicitis during the pandemic. Questions were divided into baseline information, hospital organization and screening, personal protective equipment, management and surgical approach, and patient presentation before versus during the pandemic.

resultsOf 744 answers, 709 (from 66 countries) were complete and were included in the analysis. Most hospitals were treating both patients with and those without COVID. There was variation in screening indications and modality used, with chest X-ray plus molecular testing (PCR) being the commonest (19·8 per cent). Conservative management of complicated and uncomplicated appendicitis was used by 6·6 and 2·4 per cent respectively before, but 23·7 and 5·3 per cent, during the pandemic (both P < 0·001). One-third changed their approach from laparoscopic to open surgery owing to the popular (but evidence-lacking) advice from expert groups during the initial phase of the pandemic. No agreement on how to filter surgical smoke plume during laparoscopy was identified. There was an overall reduction in the number of patients admitted with appendicitis and one-third felt that patients who did present had more severe appendicitis than they usually observe.

conclusionConservative management of mild appendicitis has been possible during the pandemic. The fact that some surgeons switched to open appendicectomy may reflect the poor guidelines that emanated in the early phase of SARS-CoV-2.

Indexed as

Attitude of Health PersonnelCOVID-19SurgeonsAnti-Bacterial AgentsAppendectomyAppendicitisCOVID-19 TestingHospital AdministrationHumansPandemicsPersonal Protective EquipmentPractice Patterns, Physicians'Surveys and QuestionnairesAnti-Bacterial Agents

Identifiers

PMID34157090
PMCPMC7675377

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.