Evidence map›Paper›PMID 34156980›Full record

ArticleThe Journal of clinical investigation2021

Association of rare predicted loss-of-function variants of influenza-related type I IFN genes with critical COVID-19 pneumonia. Reply.

Gundula Povysil, Guillaume Butler-Laporte, Ali G Gharavi, J Brent Richards, David B Goldstein, Krzysztof Kiryluk

Open access · bronzeAbstract readLetterComment
In one paragraph

Article in The Journal of clinical investigation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. The human genetic epidemiology of COVID-19.Nature reviews. Genetics · 2022
    Review
  3. Review
  4. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Gundula PovysilInstitute for Genomic Medicine, Columbia University, New York, New York, USA.
Guillaume Butler-LaporteLady Davis Institute for Medical Research, Montreal, Quebec, Canada.
Ali G GharaviDepartment of Medicine and.
J Brent RichardsLady Davis Institute for Medical Research, Montreal, Quebec, Canada.
David B GoldsteinInstitute for Genomic Medicine, Columbia University, New York, New York, USA.
Krzysztof KirylukDepartment of Medicine and.
Columbia University · USJewish General Hospital · CAKing's College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

COVID-19Influenza, HumanInterferon Type IHumansSARS-CoV-2Interferon Type IGenetic variationInfectious disease

Identifiers

PMID34156980
PMCPMC8321563
OpenAlexW3176503729

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.