Trial reportAmerican journal of respiratory and critical care medicine2021
Physiological Traits and Adherence to Sleep Apnea Therapy in Individuals with Coronary Artery Disease.
Registry-linked trialOpen access · greenAbstract readRandomized Controlled Trial
In one paragraph
Trial report in American journal of respiratory and critical care medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05067088 (Novel physIologiC prEdictors of Positive Airway Pressure Effectiveness), which is not on this map. Cited by 34 papers, 2 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 2 pooled it
4.4field-weighted citation impact, top 4% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Novel physIologiC prEdictors of Positive Airway Pressure Effectiveness: NICEPAP Study Prospective Cohort
Who cites it
34 citing papers in PubMed, 2 syntheses or guidelines pooled it, 50 citations in OpenAlex.
- Effects of continuous positive airway pressure therapy on inflammatory markers in patients with obstructive sleep apnea: a meta-analysis of randomized controlled trials.Sleep & breathing = Schlaf & Atmung · 2025Pooled it
- Association of Obstructive Sleep Apnea Syndrome (OSA/OSAHS) with Coronary Atherosclerosis Risk: Systematic Review and Meta-Analysis.Computational and mathematical methods in medicine · 2022Pooled it
- Aroxybutynin and atomoxetine (AD109) for obstructive sleep apnea: a randomized phase 3 trial (SynAIRgy).American journal of respiratory and critical care medicine · 2026Trial
- Arousal threshold modifies the effect of CPAP on executive function among individuals with obstructive sleep apnoea.The European respiratory journal · 2025Trial
- Morning Chronotype Is Associated with Improved Adherence to Continuous Positive Airway Pressure among Individuals with Obstructive Sleep Apnea.Annals of the American Thoracic Society · 2023Trial
- Rethinking Long-Term Follow-Up of CPAP Therapy in Obstructive Sleep Apnea: Toward Personalized and Integrated Care.Healthcare (Basel, Switzerland) · 2026Review
- Mechanisms of upper airway muscle control in sleep reveal therapeutic targets for obstructive sleep apnea.American journal of respiratory cell and molecular biology · 2026Review
- The upper airway in obstructive sleep apnoea: state of the art.European respiratory review : an official journal of the European Respiratory Society · 2026Review
- OSA Endotyping as Targets for Treatment. How Far Have We Come?Respirology (Carlton, Vic.) · 2026Review
- Increased Vascular Endothelial Growth Factor Receptor 2 Levels Are Associated With a Higher Occurrence of Coronary Artery Disease in Patients With Obstructive Sleep Apnea.Reviews in cardiovascular medicine · 2026Article
- Review
- Sleep Apnea Pathophysiology in Patients with a History of COVID-19.Journal of clinical medicine · 2026Article
- Research Priorities for Translating Endophenotyping of Adult Obstructive Sleep Apnea to the Clinic: An Official American Thoracic Society Research Statement.American journal of respiratory and critical care medicine · 2025Article
- Effects of Melatonin-Loaded Poly(N-vinylcaprolactam) Transdermal Gel on Sleep Quality.Gels (Basel, Switzerland) · 2025Article
- Increased MyocardialInternational journal of molecular sciences · 2025Article
- MyocardialAntioxidants (Basel, Switzerland) · 2025Article
- The Arousal Threshold: The "Weakest Link" in Obstructive Sleep Apnea Pathogenesis?American journal of respiratory and critical care medicine · 2024Article
- Breathless Nights and Cardiac Frights-How Snoring Is Breaking Hearts.Biomedicines · 2024Article
- Novel physiologic predictors of positive airway pressure effectiveness (NICEPAP) study: rationale, design and methods.Sleep & breathing = Schlaf & Atmung · 2024Observational
- Does obstructive sleep apnea-induced intermittent hypoxia increase the incidence of solitary pulmonary nodules, thyroid nodules, and other disorders? A retrospective study based on 750 cardiovascular disease patients.Sleep & breathing = Schlaf & Atmung · 2024Article
Corrections and comments
- Commented on by
Authors and funding
10 authors at 5 institutions in 4 countries.
Andrey V ZinchukDepartment of Internal Medicine, School of Medicine.ORCID 0000-0003-0488-9778
Jen-Hwa ChuDepartment of Internal Medicine, School of Medicine.
Jiasheng LiangDepartment of Internal Medicine, School of Medicine.
Yeliz CelikKoc University Research Center for Translational Medicine, Koc University, Istanbul, Turkey.
Sara Op de BeeckDepartment of Translational Neurosciences, Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium.ORCID 0000-0002-5978-9814
Nancy S RedekerDivision of Acute Care/Health Systems, Yale School of Nursing, Yale University, New Haven, Connecticut.
Andrew WellmanDivision of Sleep and Circadian Disorders, Brigham and Women's Hospital and Harvard Medical School, Harvard University, Boston, Massachusetts.
H Klar YaggiDepartment of Internal Medicine, School of Medicine.
Yüksel PekerKoc University Research Center for Translational Medicine, Koc University, Istanbul, Turkey.
Scott A SandsDivision of Sleep and Circadian Disorders, Brigham and Women's Hospital and Harvard Medical School, Harvard University, Boston, Massachusetts.
Brigham and Women's Hospital · USKoç University · TRUniversity of Antwerp · BEVA Connecticut Healthcare System · USYale University · US
Funding
Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9MProject 5: Novel strategies to prevent opioid-induced hypoventilation during sleep and identification of underlying mechanismsP01HL149630 · NHLBI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI CLIFFORD B SAPER · 2020 to 2026
$22.3MValidation of a Phenotype Model to Predict Response to Alternative OSA TreatmentsR01HL102321 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI WELLMAN, DAVID ANDREW · 2011 to 2025
$7.3MDetermination of the site of pharyngeal collapse in Obstructive Sleep Apnea patients from snoring soundsR01HL128658 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI WELLMAN, DAVID ANDREW · 2016 to 2025
$4.3MA Novel Pharmacological Therapy for Obstructive Sleep ApneaR01HL146697 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI SANDS, SCOTT A · 2019 to 2023
$3.4MNovel physiologiC prEdictors of Positive Airway Pressure effectiveness: NICE-PAP study.K23HL159259 · NHLBI · YALE UNIVERSITY · PI ZINCHUK, ANDREY · 2021 to 2025
$843kMentoring in Sleep Research and Sleep Interventions in Heart Disease, and StrokeK24HL132093 · NHLBI · YALE UNIVERSITY · PI YAGGI, HENRY KLAR · 2016 to 2020
$336kNCATS NIH HHS UL1 TR001863NHLBI NIH HHS K23 HL159259NHLBI NIH HHS K24 HL132093NHLBI NIH HHS L30 HL143623NHLBI NIH HHS P01 HL149630NHLBI NIH HHS R01 HL102321NHLBI NIH HHS R01 HL128658NHLBI NIH HHS R01 HL146697
Abstract
PubMed holds no abstract for this paper.
Indexed as
Continuous Positive Airway PressurePatient ComplianceAgedCoronary Artery DiseaseFemaleFollow-Up StudiesHumansLinear ModelsMaleMiddle AgedPolysomnographySleep Apnea, Obstructiveadherencearousal thresholdcoronary artery diseaseobstructive sleep apneaphysiologic traits
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
NCT05067088ClinicalTrials.gov
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.