Evidence map›Paper›PMID 34156827›Full record

ArticleBiochemistry2021

Structural Insight into the Substrate Scope of Viperin and Viperin-like Enzymes from Three Domains of Life.

Jake C Lachowicz, Anthony S Gizzi, Steven C Almo, Tyler L Grove

Open access · greenAbstract read
In one paragraph

Article in Biochemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 58 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jake C LachowiczDepartment of Biochemistry, Albert Einstein College of Medicine, Bronx, New York 10461, United States.
Anthony S GizziDepartment of Biochemistry, Albert Einstein College of Medicine, Bronx, New York 10461, United States.ORCID 0000-0002-2838-5358
Steven C AlmoDepartment of Biochemistry, Albert Einstein College of Medicine, Bronx, New York 10461, United States.
Tyler L GroveDepartment of Biochemistry, Albert Einstein College of Medicine, Bronx, New York 10461, United States.ORCID 0000-0002-4763-0646
Albert Einstein College of Medicine · US

Funding

X-ray Scattering Technology CoreP30GM133893 · NIGMS · BROOKHAVEN SCIENCE ASSOC-BROOKHAVEN LAB · PI Sean McSweeney · 2019 to 2026
$38.6M
Core H: MicrobiologyU54GM093342 · NIGMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI CRONAN, JOHN E. · 2010 to 2015
$34.6M
The NYSGRC: A Large Scale Center for PSI:BiologyU54GM094662 · NIGMS · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI SEIDEL, RONALD D · 2010 to 2014
$32.6M
TRAINING PROGRAM IN CELLULAR &MOLEC. BIOLOGY &GENETICST32GM007491 · NIGMS · YESHIVA UNIVERSITY · PI QUERY, CHARLES C · 1985 to 2021
$17.0M
Protein/Structure CoreP01GM118303 · NIGMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI GERLT, JOHN A · 2016 to 2020
$11.4M
Function and Mechanism of Viperin, a radical SAM antiviral proteinR21AI133329 · NIAID · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI ALMO, STEVEN C., GROVE, TYLER L · 2017 to 2018
$459k
NIAID NIH HHS R21 AI133329NIGMS NIH HHS P01 GM118303NIGMS NIH HHS P30 GM133893NIGMS NIH HHS T32 GM007491NIGMS NIH HHS U54 GM093342NIGMS NIH HHS U54 GM094662
6 · The paper itself

Abstract

Viperin is a member of the radical

Indexed as

Amino Acid SequenceAnimalsArchaeal ProteinsBacteriaBacterial ProteinsBiocatalysisFungal ProteinsHumansHypocreaMethanomicrobiaceaeMiceNucleotidesOxidoreductases Acting on CH-CH Group DonorsProtein BindingSubstrate SpecificityArchaeal ProteinsBacterial ProteinsFungal ProteinsNucleotidesOxidoreductases Acting on CH-CH Group Donors

Identifiers

PMID34156827
PMCPMC8672371
OpenAlexW3176989393

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.