ArticleCerebellum (London, England)2022
Can Dyssynergia of Vestibulosympathetic and Baroreflexes Cause Vestibular Syncope? The Hypothesis Based on the Velocity-Storage Function.
Article in Cerebellum (London, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 19 citations in OpenAlex.
- Heart rate variability dynamics during virtual reality roller coaster experience: correlations with vestibular function and motion sickness susceptibility.Scientific reports · 2026Article
- Update on Clinical Physiology and Pathomechanisms for Vestibulo-Autonomic Interplay.Cerebellum (London, England) · 2025Review
- Differential diagnosis of orthostatic dizziness with persistent postural-perceptual dizziness and its underlying mechanisms.Frontiers in neurology · 2025Review
- Disrupted Rotational Perception During Simultaneous Stimulation of Rotation and Inertia.Cerebellum (London, England) · 2024Article
- Presence of Spontaneous Nystagmus, Benign Paroxysmal Positional Vertigo, and Tumarkin Fall in Patients With Primary Headache and Their Responses to Caloric and Video Head Impulse Tests.Journal of clinical medicine research · 2024Article
- A study of otolith function in patients with orthostatic dizziness.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2023Article
- Periodic vertigo and downbeat nystagmus while supine: Dysfunction of Purkinje cells coding gravity.Annals of clinical and translational neurology · 2023Article
- Augmented ocular vestibular-evoked myogenic potentials in postural orthostatic tachycardia syndrome.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2023Article
- Effect of a False Inertial Cue in the Velocity-Storage Circuit on Head Posture and Inertia Perception.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Utricular dysfunction in patients with orthostatic hypotension.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2022Article
- The role of otolith reflexes in orthostatic intolerance.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2022Article
- Vestibular syncope: clinical characteristics and mechanism.Annals of clinical and translational neurology · 2022Article
- Impaired Duration Perception in Patients With Unilateral Vestibulopathy During Whole-Body Rotation.Frontiers in integrative neuroscience · 2022Article
- Toward personalized medicine for mal de débarquement syndrome.Frontiers in neurologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 5 institutions in 3 countries.
Funding
Abstract
The mechanism of vestibular syncope, the syncope occurring during the vertigo attacks, remains uncertain. This study aims to clarify the mechanism of vestibular syncope by pursuing the function of vestibular system in cardiovascular autonomic control and by defining neuro-hemodynamic changes in vestibular syncope. By integrating the velocity-storage (VS) circuit in the brainstem and cerebellum, we propose that the vestibular syncope develops as a result of dyssynergia of the vestibulosympathetic and baroreflexes in which centrally estimated downward inertial acceleration during the vertigo attacks acts as a trigger. Recognition of the vestibular disorders as a possible cause of syncope would allow proper managements for prevention of further syncope and related complications in patients with vestibular disorders.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.